Genome Signature HRD Test: Comprehensive Genetic Analysis for Personalized Cancer Treatment
Understanding Genome Signature HRD Testing
The Genome Signature HRD test represents a groundbreaking advancement in precision oncology, offering comprehensive genomic profiling to identify homologous recombination deficiency. This sophisticated diagnostic tool utilizes next-generation sequencing (NGS) technology to analyze genetic mutations that impact DNA repair mechanisms, providing crucial insights for targeted cancer therapy selection.
What Does the Genome Signature HRD Test Measure?
This advanced genetic test specifically evaluates:
- Homologous recombination deficiency (HRD) status
- DNA repair pathway mutations
- Genomic instability patterns
- Specific gene alterations affecting DNA damage response
- Tumor mutational burden related to HRD
Who Should Consider Genome Signature HRD Testing?
This test is particularly recommended for individuals with:
- Ovarian cancer patients considering PARP inhibitor therapy
- Breast cancer cases with potential hereditary components
- Pancreatic cancer requiring targeted treatment options
- Prostate cancer patients exploring advanced therapeutic approaches
- Individuals with family history of BRCA-related cancers
- Patients with recurrent or treatment-resistant cancers
Clinical Indications and Symptoms
Consider this test if you experience:
- Diagnosis of high-grade serous ovarian cancer
- Triple-negative breast cancer diagnosis
- Metastatic castration-resistant prostate cancer
- Pancreatic adenocarcinoma requiring treatment planning
- Family history suggestive of hereditary cancer syndromes
Benefits of Genome Signature HRD Testing
Choosing the Genome Signature HRD test provides numerous advantages:
- Personalized Treatment Planning: Identifies patients who may benefit from PARP inhibitor therapies
- Improved Outcomes: Helps select the most effective targeted treatments
- Comprehensive Analysis: Provides detailed genetic profiling beyond standard testing
- Treatment Optimization: Reduces trial-and-error approaches to cancer therapy
- Family Risk Assessment: Offers insights into hereditary cancer risks
- Clinical Trial Eligibility: May qualify patients for specific research studies
Understanding Your Test Results
Your Genome Signature HRD results will provide:
- HRD Status: Positive or negative indication of homologous recombination deficiency
- Genomic Instability Score: Quantitative assessment of chromosomal abnormalities
- Mutation Analysis: Detailed report on specific gene alterations
- Clinical Interpretation: Expert analysis of results in treatment context
- Therapeutic Recommendations: Guidance on potential treatment options
Results are typically available within 3-4 weeks and should be reviewed with your healthcare provider to develop an appropriate treatment plan based on your specific genetic profile.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | Genome Signature HRD Test |
| Regular Price | $9,000 USD |
| Discount Price | $6,750 USD |
| Turnaround Time | 3-4 weeks |
| Sample Type | Tumor tissue + Peripheral Blood |
| Test Components | Paraffin embedded tissue blocks + EDTA Vacutainer (2ml) + Streck tube |
Pre-Test Instructions
The Genome Signature HRD test requires a doctor’s prescription for most cases. Please note that prescriptions are not applicable for surgery and pregnancy cases or individuals planning to travel abroad. Consult with your healthcare provider to determine if this test is appropriate for your specific medical situation.
Nationwide Testing Availability
GGC DNA has testing facilities across the United States, ensuring convenient access to the Genome Signature HRD test in major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and the Midwest
- Houston and Texas metropolitan areas
- Miami and Florida locations
- Seattle and Pacific Northwest centers
- Boston and New England facilities
Take the Next Step in Your Healthcare Journey
Don’t wait to get the comprehensive genetic insights you need for informed treatment decisions. Our expert team is ready to assist you with scheduling your Genome Signature HRD test and answering any questions about the process.
Call or WhatsApp us today at +1(267) 388-9828 to book your test or learn more about how the Genome Signature HRD test can benefit your treatment planning.
Take control of your cancer treatment journey with advanced genetic testing from GGC DNA – your partner in precision oncology care.

