GDNF Gene Hirschsprung Disease Type 3 Susceptibility NGS Genetic DNA Test
Comprehensive Genetic Analysis for Pediatric Gastrointestinal Disorders
The GDNF Gene Hirschsprung Disease Type 3 Susceptibility NGS Genetic DNA Test represents a cutting-edge approach to diagnosing and understanding hereditary gastrointestinal conditions in pediatric patients. This specialized genetic test focuses on identifying mutations in the GDNF (glial cell line-derived neurotrophic factor) gene, which plays a crucial role in the development of the enteric nervous system – the complex network of neurons that controls gastrointestinal function.
What This Test Measures and Detects
Our advanced NGS Genetic DNA Test specifically targets:
- Sequence variations and mutations in the GDNF gene
- Single nucleotide polymorphisms (SNPs) associated with Hirschsprung disease susceptibility
- Copy number variations affecting GDNF gene expression
- Genetic markers linked to enteric nervous system development
- Inheritance patterns for family risk assessment
Who Should Consider This Genetic Test
This test is particularly recommended for:
- Infants and children presenting with symptoms of intestinal obstruction
- Newborns with delayed passage of meconium (beyond 48 hours)
- Children experiencing chronic constipation unresponsive to conventional treatments
- Patients with family history of Hirschsprung disease or related gastrointestinal disorders
- Individuals with suspected congenital megacolon or intestinal dysmotility
- Patients undergoing evaluation for neurocristopathies
Clinical Benefits of GDNF Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Early Diagnosis: Enables prompt identification of Hirschsprung disease susceptibility
- Personalized Treatment: Guides targeted therapeutic interventions based on genetic profile
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Risk Assessment: Helps determine recurrence risks for future pregnancies
- Comprehensive Care: Facilitates multidisciplinary approach involving pediatric surgeons, gastroenterologists, and genetic specialists
Understanding Your Test Results
Our genetic counseling team provides comprehensive interpretation of your results:
- Positive Result: Indicates presence of GDNF gene mutations associated with increased Hirschsprung disease risk
- Negative Result: Suggests absence of tested mutations, though other genetic factors may still contribute
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Identifies individuals who may pass genetic mutations to offspring
All results are accompanied by detailed genetic counseling to ensure proper understanding and appropriate next steps.
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | GDNF Gene Hirschsprung Disease Type 3 Susceptibility NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have comprehensive testing facilities across the United States, with specialized centers in:
- New York City and surrounding metropolitan areas
- Los Angeles and Southern California regions
- Chicago and Midwest locations
- Houston, Dallas, and Texas facilities
- Phoenix, Arizona and Southwest centers
- All other major metropolitan areas nationwide
Pre-Test Requirements
To ensure accurate results and comprehensive care, we recommend:
- Complete clinical history of the patient
- Genetic counseling session prior to testing
- Development of detailed family pedigree chart
- Documentation of affected family members
- Comprehensive gastrointestinal evaluation
Take Control of Your Genetic Health Today
Don’t let uncertainty about hereditary conditions affect your family’s future. Our GDNF Gene Hirschsprung Disease Type 3 Susceptibility NGS Genetic DNA Test provides the clarity and information you need for informed healthcare decisions. With our advanced NGS technology and expert genetic counseling team, you can trust in accurate, reliable results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test or speak with our genetic counseling specialists. Take the first step toward understanding your genetic health and ensuring the best possible outcomes for your family.
Our dedicated team of pediatric genetic specialists, gastroenterologists, and genetic counselors are committed to providing comprehensive care and support throughout your testing journey. With convenient locations across the United States and flexible sample collection options, accessing this vital genetic information has never been easier.
