FLT3 ITD D835Y Mutation Detection Test
Comprehensive Genetic Analysis for Leukemia Management
The FLT3 ITD D835Y Mutation Detection test represents a breakthrough in personalized cancer care, specifically designed for patients diagnosed with acute myeloid leukemia (AML). This sophisticated genetic analysis provides critical information that directly influences treatment strategies and prognostic assessments, enabling healthcare providers to deliver targeted, effective care based on individual genetic profiles.
What Does This Test Measure?
This advanced molecular diagnostic test specifically identifies two crucial types of mutations in the FLT3 (FMS-like tyrosine kinase 3) gene:
- Internal Tandem Duplications (ITD): These mutations involve the duplication of genetic material within the FLT3 gene, leading to uncontrolled cell growth and proliferation
- Tyrosine Kinase Domain Mutations (D835Y): Point mutations that affect the kinase domain of the FLT3 protein, resulting in continuous activation of signaling pathways
Both mutation types contribute to the aggressive nature of AML and significantly impact treatment response and overall survival rates.
Who Should Consider This Test?
This genetic analysis is particularly important for:
- Newly diagnosed acute myeloid leukemia patients
- Individuals experiencing unexplained fatigue, bruising, or frequent infections
- Patients with abnormal blood cell counts requiring further investigation
- Those with family history of hematological malignancies
- Patients being evaluated for targeted therapy options
- Individuals requiring prognostic assessment for treatment planning
Key Benefits of FLT3 Mutation Testing
- Personalized Treatment Planning: Results guide the selection of targeted therapies specifically designed for FLT3-mutated AML
- Prognostic Information: Helps determine disease aggressiveness and expected treatment response
- Monitoring Disease Progression: Enables tracking of mutation status throughout treatment
- Improved Outcomes: Facilitates early intervention with appropriate targeted therapies
- Minimized Side Effects: Reduces exposure to ineffective treatments and their associated risks
Understanding Your Test Results
Your FLT3 mutation analysis results will fall into one of several categories:
- Positive for FLT3-ITD Mutation: Indicates the presence of internal tandem duplications, typically associated with more aggressive disease and poorer prognosis
- Positive for FLT3-TKD Mutation (D835Y): Shows tyrosine kinase domain mutations that may respond to specific targeted inhibitors
- Double Positive: Presence of both ITD and TKD mutations requiring comprehensive treatment strategies
- Negative Result: No FLT3 mutations detected, suggesting alternative treatment approaches may be more appropriate
Your healthcare provider will interpret these results in the context of your complete clinical picture to develop the most effective treatment plan.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | FLT3 ITD D835Y Mutation Detection |
| Regular Price | $200 USD |
| Discount Price | $150 USD |
| Turnaround Time | 3-4 days |
| Sample Type | Bone marrow / Peripheral blood (Transport immediately) |
| Test Components | EDTA Vacutainer (2ml) |
| Testing Method | End Point PCR |
Pre-Test Instructions
The FLT3 ITD D835Y Mutation Detection test requires a doctor’s prescription for most cases. Please note that prescriptions are not applicable for surgery and pregnancy cases or individuals planning to travel abroad. Our team will guide you through the sample collection process and ensure proper handling of your genetic material for accurate results.
Nationwide Accessibility
We have testing facilities conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures you can access this critical genetic testing regardless of your location.
Take Control of Your Health Today
Don’t leave your leukemia treatment to chance. The FLT3 ITD D835Y Mutation Detection test provides the genetic insights needed for personalized, effective cancer care. Our experienced genetic counselors and healthcare professionals are ready to assist you throughout the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your FLT3 mutation analysis and take the first step toward targeted leukemia treatment.
Early detection and personalized treatment planning can make a significant difference in your leukemia journey. Book your test now and gain the genetic information necessary for optimal care.
