FLI1 Gene Platelet Dense Granule Secretion Defect Excessive Bleeding NGS Genetic DNA Test
Comprehensive Genetic Analysis for Bleeding Disorders
The FLI1 Gene Platelet Dense Granule Secretion Defect Excessive Bleeding NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for bleeding disorders. This advanced test specifically targets the FLI1 gene, which plays a critical role in platelet development and function. Platelet dense granule secretion defects are rare inherited conditions that can lead to significant bleeding complications, and early genetic identification is essential for proper management and treatment planning.
What Does This Test Measure and Detect?
This comprehensive genetic test utilizes Next-Generation Sequencing (NGS) technology to analyze the FLI1 gene for mutations associated with platelet dense granule secretion defects. The test specifically detects:
- Point mutations in the FLI1 gene coding regions
- Insertions and deletions affecting gene function
- Regulatory region variants impacting gene expression
- Pathogenic variants linked to impaired platelet dense granule secretion
- Genetic markers associated with inherited bleeding tendencies
Who Should Consider This Genetic Test?
Clinical Indications and Symptoms
This test is recommended for individuals experiencing:
- Unexplained excessive bleeding following minor injuries or surgeries
- Frequent nosebleeds without apparent cause
- Easy bruising with minimal trauma
- Prolonged bleeding from minor cuts or abrasions
- Heavy or prolonged menstrual bleeding in women
- Family history of bleeding disorders or platelet function defects
- Abnormal platelet aggregation test results
- Suspected inherited platelet disorders
Key Benefits of FLI1 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Precise identification of FLI1 gene mutations confirms the underlying cause of bleeding symptoms
- Personalized Treatment: Genetic results guide targeted therapeutic approaches and medication selection
- Family Planning: Enables informed reproductive decisions and genetic counseling for at-risk family members
- Proactive Management: Early detection allows for preventive measures before surgical procedures or dental work
- Comprehensive Assessment: NGS technology provides thorough analysis of the entire FLI1 gene region
- Clinical Correlation: Results help hematologists correlate genetic findings with clinical bleeding patterns
Understanding Your Test Results
Interpretation Guidelines
Your FLI1 genetic test results will be carefully analyzed and interpreted by our expert genetic counselors and hematologists:
- Positive Result: Indicates the presence of pathogenic FLI1 gene mutations associated with platelet dense granule secretion defects. This confirms the genetic basis of bleeding symptoms and guides specific treatment recommendations.
- Negative Result: Suggests no detectable FLI1 gene mutations were found. However, other genetic or acquired causes of bleeding disorders may still be present and require further investigation.
- Variant of Uncertain Significance (VUS): Some genetic changes may have unclear clinical implications. These results require careful clinical correlation and may benefit from family studies.
- Carrier Status: Identifies individuals who carry one copy of a mutated gene but may not show symptoms, important for family planning considerations.
Test Specifications and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | FLI1 Gene Platelet Dense Granule Secretion Defect Excessive Bleeding NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Hematology Genetics |
Pre-Test Requirements and Preparation
To ensure accurate results and comprehensive assessment, the following pre-test requirements are essential:
- Complete clinical history documentation of bleeding symptoms and patterns
- Genetic counseling session to discuss test implications and family history
- Development of detailed pedigree chart documenting affected family members
- Review of previous hematological testing and bleeding assessment results
- Discussion of potential outcomes and their clinical significance
Nationwide Testing Availability
We have conveniently located testing facilities across the United States, including major metropolitan areas such as New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible testing for patients nationwide.
Take Control of Your Health Today
Don’t let unexplained bleeding symptoms compromise your quality of life. The FLI1 Gene Platelet Dense Granule Secretion Defect Excessive Bleeding NGS Genetic DNA Test provides the definitive genetic information needed for accurate diagnosis and effective management of bleeding disorders. Our team of expert hematologists and genetic counselors is ready to guide you through the testing process and help interpret your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic testing appointment or to speak with our genetic counseling team. Take the first step toward understanding your bleeding symptoms and developing a personalized treatment plan.
