FGA Gene Afibrinogenemia Congenital NGS Genetic DNA Test
Comprehensive Genetic Testing for Inherited Bleeding Disorders
The FGA Gene Afibrinogenemia Congenital NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for hereditary bleeding conditions. This advanced genetic analysis specifically targets the FGA gene, which encodes the alpha chain of fibrinogen – a critical protein essential for proper blood coagulation. Congenital afibrinogenemia is a rare autosomal recessive disorder characterized by the complete absence of fibrinogen in the bloodstream, leading to severe bleeding tendencies that can manifest from birth throughout an individual’s lifetime.
What Does This Test Measure and Detect?
This sophisticated genetic test employs Next-Generation Sequencing (NGS) technology to comprehensively analyze the entire FGA gene for pathogenic variants. The test specifically detects:
- Point mutations, deletions, and insertions in the FGA gene
- Nonsense and missense mutations affecting fibrinogen production
- Splice site variants that disrupt proper gene expression
- Frameshift mutations leading to premature stop codons
- Compound heterozygous mutations in affected individuals
The test provides definitive molecular diagnosis by identifying the specific genetic alterations responsible for impaired fibrinogen synthesis, enabling precise characterization of the underlying genetic defect.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals presenting with:
- Unexplained prolonged bleeding from minor injuries or surgical procedures
- Spontaneous bleeding into joints, muscles, or internal organs
- Excessive bruising without significant trauma
- Family history of bleeding disorders or consanguineous parents
- Abnormal coagulation test results showing prolonged clotting times
- Umbilical stump bleeding in newborns
- Recurrent miscarriages in women with bleeding tendencies
- Pre-surgical screening for individuals with suspected bleeding disorders
Clinical Benefits of Genetic Testing
Undergoing the FGA Gene Afibrinogenemia test provides numerous clinical advantages:
- Accurate Diagnosis: Provides definitive molecular confirmation of congenital afibrinogenemia
- Personalized Treatment: Enables tailored fibrinogen replacement therapy protocols
- Genetic Counseling: Facilitates informed family planning decisions
- Proactive Management: Allows for preventive measures before surgical procedures
- Carrier Detection: Identifies asymptomatic carriers within families
- Prenatal Diagnosis: Enables early detection in subsequent pregnancies
- Differential Diagnosis: Distinguishes afibrinogenemia from other coagulation disorders
Understanding Your Test Results
Your genetic test report will provide comprehensive information about your FGA gene status:
- Normal Result: No pathogenic variants detected in the FGA gene
- Heterozygous Carrier: One mutated copy of FGA gene identified
- Affected Individual: Two pathogenic mutations confirmed in FGA gene
- Variant of Uncertain Significance: Genetic change identified with unknown clinical impact
All positive results include detailed interpretation by our board-certified genetic counselors and hematologists, providing clear guidance on next steps, treatment options, and family screening recommendations.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take Control of Your Genetic Health Today
Don’t let uncertainty about inherited bleeding disorders affect your quality of life. Our comprehensive FGA Gene Afibrinogenemia Congenital NGS Genetic DNA Test provides the clarity you need for informed healthcare decisions. With our discounted price of $500 USD and extensive nationwide coverage, advanced genetic testing has never been more accessible.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our dedicated genetic specialists are ready to guide you through every step of the testing process and help you understand your results with compassion and expertise.
