FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test
Comprehensive Genetic Testing for Immune System Disorders
The FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare immune disorders. This advanced test specifically targets mutations in the FERMT3 gene, which plays a critical role in leukocyte adhesion and immune system function. Leukocyte Adhesion Deficiency Type 3 (LAD-III) is a rare autosomal recessive disorder characterized by impaired leukocyte migration and platelet function, leading to severe immune deficiencies and bleeding tendencies.
What Does This Test Measure and Detect?
This comprehensive genetic analysis utilizes Next-Generation Sequencing (NGS) technology to examine the entire FERMT3 gene for pathogenic variants. The test specifically detects:
- Point mutations, insertions, and deletions in the FERMT3 gene
- Genetic variations affecting kindlin-3 protein function
- Mutations responsible for impaired integrin activation
- Genetic markers associated with leukocyte adhesion defects
- Variants linked to platelet function abnormalities
Who Should Consider This Genetic Test?
This test is recommended for individuals presenting with the following symptoms or clinical indications:
- Recurrent bacterial and fungal infections from early childhood
- Delayed umbilical cord separation beyond 3 weeks
- Persistent leukocytosis with elevated neutrophil counts
- Abnormal bleeding tendencies and easy bruising
- Poor wound healing and impaired inflammatory responses
- Family history of immune deficiency disorders
- Consanguineous parentage with suspected genetic disorders
- Unexplained recurrent skin infections and abscesses
Clinical Benefits of Genetic Testing
Undergoing the FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test provides numerous clinical advantages:
- Definitive Diagnosis: Confirms or rules out LAD-III with high accuracy
- Personalized Treatment: Enables targeted therapeutic interventions
- Family Planning: Provides crucial information for genetic counseling
- Early Intervention: Facilitates proactive management of complications
- Improved Prognosis: Guides appropriate medical care and monitoring
- Research Contribution: Advances understanding of rare immune disorders
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of genetic specialists and immunologists. The report will include:
- Positive Result: Indicates the presence of pathogenic FERMT3 gene mutations, confirming LAD-III diagnosis
- Negative Result: Suggests absence of known disease-causing mutations in the FERMT3 gene
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical implications requiring further evaluation
- Carrier Status: Determines if you carry one copy of a mutated gene without showing symptoms
All positive results include comprehensive genetic counseling to discuss implications, treatment options, and family planning considerations.
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialties Involved | Dermatology, Genetics, Immunology |
Pre-Test Requirements
Before undergoing testing, patients should provide:
- Complete clinical history including infection patterns and bleeding tendencies
- Detailed family medical history with pedigree chart
- Previous laboratory results and immune function tests
- Genetic counseling session to discuss test implications and expectations
Nationwide Testing Availability
We have testing facilities conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take Control of Your Health Today
Don’t let uncertainty about your immune health continue. The FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test provides the clarity needed for proper diagnosis and treatment planning. Our team of genetic counselors and immunology specialists are ready to guide you through the testing process and help interpret your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test or to speak with our genetic counseling team. Take the first step toward understanding your genetic health and receiving the personalized care you deserve.
