FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Immune System Disorders
The FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying mutations in the FERMT3 gene, which plays a critical role in immune system function and blood clotting mechanisms. This sophisticated genetic test utilizes next-generation sequencing technology to provide comprehensive analysis of the FERMT3 gene, enabling accurate diagnosis of Leukocyte Adhesion Deficiency Type 3 (LAD-III), a rare but serious inherited disorder affecting both immune response and platelet function.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets and analyzes the FERMT3 gene, which encodes the kindlin-3 protein essential for proper integrin activation in white blood cells and platelets. The test detects:
- Point mutations, deletions, and insertions in the FERMT3 gene
- Genetic variations affecting kindlin-3 protein function
- Mutations responsible for impaired leukocyte adhesion and migration
- Genetic defects causing platelet aggregation abnormalities
- Inherited patterns of LAD-III transmission
Who Should Consider This Genetic Test?
This test is recommended for individuals presenting with specific clinical symptoms or family history patterns:
- Recurrent bacterial infections starting in infancy or early childhood
- Delayed umbilical cord separation beyond 3 weeks after birth
- Abnormal bleeding tendencies and easy bruising
- Poor wound healing and persistent skin infections
- Family history of immune deficiency disorders
- Unexplained leukocytosis with elevated neutrophil counts
- Suspected Glanzmann thrombasthenia-like bleeding symptoms
- Consanguineous parents or known carrier status in family
Clinical Benefits of FERMT3 Genetic Testing
Early and accurate diagnosis through FERMT3 genetic testing provides numerous clinical advantages:
- Definitive Diagnosis: Confirms LAD-III diagnosis, distinguishing it from other immune deficiencies
- Personalized Treatment: Enables targeted therapeutic approaches based on genetic findings
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Proactive Management: Allows early intervention to prevent severe infections and bleeding complications
- Stem Cell Transplant Guidance: Informs decisions regarding curative hematopoietic stem cell transplantation
- Carrier Detection: Identifies asymptomatic carriers within families
Understanding Your Test Results
Your FERMT3 genetic test results will be carefully interpreted by our expert genetic counselors and hematologists:
- Positive Result: Identifies pathogenic mutations confirming LAD-III diagnosis, requiring comprehensive hematology and immunology management
- Negative Result: No FERMT3 mutations detected, suggesting alternative diagnoses should be considered
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical impact, requiring additional family studies
- Carrier Status: Identifies individuals with one mutated copy who may pass the condition to offspring
All positive results include detailed genetic counseling sessions to discuss implications, treatment options, and family testing recommendations.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your location.
Take Control of Your Genetic Health Today
Don’t let uncertainty about immune system disorders or bleeding tendencies affect your quality of life. Our FERMT3 Gene Leukocyte Adhesion Deficiency Type 3 NGS Genetic DNA Test provides the clarity needed for proper diagnosis and management. With results available in 3-4 weeks and multiple sample collection options including blood, extracted DNA, or blood spots on FTA cards, getting tested has never been more convenient.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our expert team is ready to guide you through every step of the testing process and help you understand your results.
