CXCR4 Gene WHIM Syndrome NGS Genetic DNA Test
Comprehensive Genetic Testing for WHIM Syndrome
The CXCR4 Gene WHIM Syndrome NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying mutations in the CXCR4 gene that cause WHIM syndrome (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis). This rare primary immunodeficiency disorder affects multiple body systems, particularly the immune system and bone marrow function. Our advanced Next-Generation Sequencing (NGS) technology provides unparalleled accuracy in detecting genetic variations that traditional testing methods might miss.
What Does This Test Measure?
This comprehensive genetic analysis specifically targets the CXCR4 gene, which encodes the C-X-C chemokine receptor type 4 protein. The test detects:
- Point mutations and single nucleotide variants in the CXCR4 gene
- Frameshift mutations affecting protein structure
- Gain-of-function mutations that lead to enhanced receptor signaling
- Genetic variations associated with impaired neutrophil trafficking
- Mutations causing abnormal immune cell migration and retention
Who Should Consider This Test?
This genetic test is particularly important for individuals presenting with:
- Recurrent bacterial infections from childhood
- Persistent warts and human papillomavirus infections
- Low levels of immunoglobulins (hypogammaglobulinemia)
- Neutropenia with bone marrow showing myelokathexis
- Family history of immunodeficiency disorders
- Unexplained chronic infections affecting multiple organ systems
- Developmental abnormalities in immune system function
Clinical Benefits of Genetic Testing
Undergoing the CXCR4 Gene WHIM Syndrome test provides numerous advantages:
- Accurate Diagnosis: Confirms WHIM syndrome with molecular precision
- Personalized Treatment: Guides targeted therapeutic approaches
- Family Planning: Provides crucial information for genetic counseling
- Prognostic Insights: Helps predict disease progression and complications
- Therapeutic Monitoring: Assists in evaluating treatment effectiveness
- Early Intervention: Enables proactive management of symptoms
Understanding Your Test Results
Our comprehensive genetic report includes detailed interpretation of your results:
- Positive Result: Indicates the presence of CXCR4 gene mutations associated with WHIM syndrome, requiring specialized immunology care
- Negative Result: Suggests absence of known WHIM syndrome mutations, though clinical correlation remains essential
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical evaluation
- Carrier Status: Determines inheritance patterns for family members
All results are accompanied by detailed explanations and recommendations for next steps, including consultation with immunology and genetics specialists.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| CXCR4 Gene WHIM Syndrome NGS Genetic DNA Test | $500 USD | $700 USD |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible genetic testing services for patients throughout the country.
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and next steps
Take Control of Your Health Today
Don’t let uncertainty about your immune health continue. The CXCR4 Gene WHIM Syndrome NGS Genetic DNA Test provides definitive answers that can transform your healthcare journey. Our experienced genetic counselors and immunology specialists are ready to support you through every step of the testing process.
Book your comprehensive genetic test now by calling +1(267) 388-9828 or schedule your appointment online. Take the first step toward understanding your genetic health and receiving personalized medical care.
