CLCF1 Gene Cold-Induced Sweating Syndrome Type 2 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Cold-Induced Sweating Syndrome
The CLCF1 Gene Cold-Induced Sweating Syndrome Type 2 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare autonomic nervous system disorders. This advanced test specifically targets mutations in the CLCF1 (Cardiotrophin-Like Cytokine Factor 1) gene, which plays a crucial role in the development and function of the autonomic nervous system. Cold-Induced Sweating Syndrome Type 2 (CISS2) is a rare genetic condition characterized by abnormal sweating patterns triggered by cold temperatures, often accompanied by distinctive facial features and developmental concerns.
What Does This Test Measure and Detect?
Our comprehensive NGS-based genetic test provides detailed analysis of the CLCF1 gene to identify:
- Point mutations and single nucleotide variants in the CLCF1 gene
- Small insertions and deletions affecting gene function
- Pathogenic variants associated with CISS2 development
- Genetic markers indicating inheritance patterns
- Specific mutations affecting cytokine signaling pathways
The test utilizes cutting-edge Next-Generation Sequencing technology to examine the entire coding region of the CLCF1 gene, ensuring comprehensive coverage and high diagnostic accuracy. This approach allows for the detection of even rare genetic variants that might be missed by conventional testing methods.
Who Should Consider This Genetic Test?
This specialized genetic test is recommended for individuals presenting with the following symptoms or clinical indications:
- Abnormal sweating patterns triggered by cold exposure
- Distinctive facial features including prominent forehead and hypertelorism
- Developmental delays or intellectual disability
- Family history of Cold-Induced Sweating Syndrome
- Unexplained autonomic nervous system dysfunction
- Pediatric patients with dysmorphic features and temperature regulation issues
- Individuals with suspected CISS2 based on clinical presentation
Key Benefits of CLCF1 Genetic Testing
Choosing our comprehensive CLCF1 genetic test provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Provides definitive genetic confirmation of CISS2, eliminating diagnostic uncertainty
- Family Planning Guidance: Helps families understand inheritance patterns and recurrence risks
- Personalized Treatment: Enables development of targeted management strategies for temperature regulation issues
- Early Intervention: Facilitates timely implementation of supportive therapies and monitoring
- Comprehensive Analysis: NGS technology ensures thorough examination of the CLCF1 gene
- Expert Interpretation: Results are analyzed by board-certified genetic specialists
Understanding Your Test Results
Our genetic counseling team provides comprehensive support in interpreting your CLCF1 test results:
- Positive Result: Indicates the presence of pathogenic mutations in the CLCF1 gene, confirming CISS2 diagnosis
- Negative Result: Suggests that CLCF1 mutations were not detected, though clinical correlation is essential
- Variant of Uncertain Significance: Some genetic changes may require additional family studies for interpretation
- Carrier Status: Identifies individuals who carry one copy of a CLCF1 mutation without showing symptoms
All results are accompanied by detailed explanations and recommendations for next steps, including referral to appropriate specialists and development of personalized management plans.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or Blood on FTA Card |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified collection centers ensures accessible testing for patients nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about Cold-Induced Sweating Syndrome Type 2 affect your quality of life. Our specialized CLCF1 genetic test provides the answers you need for informed healthcare decisions. Contact our genetic counseling team today to schedule your test and begin your journey toward accurate diagnosis and personalized care.
Call or WhatsApp us now at +1(267) 388-9828 to book your CLCF1 Genetic DNA Test and take advantage of our special discounted price of $500 USD.
