cKIT Mutation Screening Exons 9 11 13 17 AML Test - $188 USA | Acute Myeloid Leukemia Genetic Testing
CLL NGS Panel FISH KT IGHV TP53 Mutation Analysis Test - $976 USD | Comprehensive Genetic Testing for Chronic Lymphocytic Leukemia in USA CLL NGS Panel with FISH, Karyotyping, IGHV Mutation Analysis, and TP53 Mutation Analysis Original price was: $1,300.Current price is: $976.
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cKIT Mutation Screening Exons 9, 11, 13, 17 AML

Original price was: $250.Current price is: $188.

-25%

The cKIT Mutation Screening Exons 9, 11, 13, 17 AML test is a specialized genetic analysis designed to detect specific mutations in the cKIT gene associated with Acute Myeloid Leukemia. This comprehensive screening examines four critical exons (9, 11, 13, and 17) using advanced Sanger Sequencing technology to identify mutations that impact disease progression and treatment response. The test is particularly valuable for patients diagnosed with AML, especially those with core-binding factor AML subtypes, as cKIT mutations can influence prognosis and guide targeted therapy decisions. Results are typically available within 7-8 days from a simple peripheral blood sample. At only $188 USD, this test provides crucial genetic information that can significantly impact treatment planning and disease management strategies for leukemia patients across the United States.

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cKIT Mutation Screening Exons 9, 11, 13, 17 AML

Comprehensive Genetic Analysis for Acute Myeloid Leukemia

The cKIT Mutation Screening Exons 9, 11, 13, 17 AML test represents a cutting-edge genetic diagnostic tool specifically designed for patients with Acute Myeloid Leukemia. This sophisticated screening targets the cKIT gene, a critical receptor tyrosine kinase that plays a pivotal role in cell signaling, proliferation, and differentiation. When mutations occur in specific regions of this gene, particularly exons 9, 11, 13, and 17, they can significantly impact disease progression, treatment response, and overall prognosis in AML patients.

What This Test Measures and Detects

This comprehensive genetic screening utilizes advanced Sanger Sequencing technology to meticulously analyze four crucial exons of the cKIT gene:

  • Exon 9: Detects extracellular domain mutations affecting receptor dimerization
  • Exon 11: Identifies juxtamembrane domain mutations that disrupt autoinhibition
  • Exon 13: Screens for kinase domain mutations impacting ATP binding
  • Exon 17: Analyzes activation loop mutations that affect kinase activity

The test specifically looks for point mutations, insertions, and deletions that can activate the cKIT receptor, leading to uncontrolled cell growth and contributing to leukemogenesis in AML patients.

Who Should Consider This Test

This genetic screening is particularly recommended for:

  • Patients newly diagnosed with Acute Myeloid Leukemia
  • Individuals with core-binding factor AML subtypes (including t(8;21) and inv(16))
  • Patients experiencing unexplained fatigue, recurrent infections, or abnormal bleeding
  • Those with abnormal blood counts requiring further investigation
  • Individuals with a family history of hematological malignancies
  • Patients being evaluated for targeted therapy options

Clinical Benefits of cKIT Mutation Screening

Undergoing this comprehensive genetic analysis provides numerous clinical advantages:

  • Precise Prognostic Information: cKIT mutations are associated with poorer outcomes in core-binding factor AML
  • Treatment Guidance: Results can influence chemotherapy intensity decisions and stem cell transplantation considerations
  • Targeted Therapy Opportunities: Identifies patients who may benefit from tyrosine kinase inhibitors
  • Disease Monitoring: Establishes baseline mutation status for future monitoring
  • Personalized Medicine Approach: Enables tailored treatment strategies based on individual genetic profile

Understanding Your Test Results

Your cKIT mutation screening results will be carefully interpreted by our expert genetic counselors and hematologists:

  • Negative Result: No detectable mutations in the screened exons – this may indicate standard risk profile
  • Positive Result: Identified mutation(s) in one or more exons – requires detailed interpretation based on mutation type and location
  • Variant of Unknown Significance: Rare genetic changes requiring additional clinical correlation

All results are provided with comprehensive explanations and recommendations for next steps in your treatment journey. Our genetic counseling team is available to discuss your results and answer any questions you may have.

Test Pricing and Details

Test Component Details
Test Name cKIT Mutation Screening Exons 9, 11, 13, 17 AML
Regular Price $250 USD
Discount Price $188 USD
Turnaround Time 7-8 days
Sample Type Peripheral Blood (EDTA Blood 2ml)
Testing Method Sanger Sequencing

Nationwide Accessibility

We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.

Take the Next Step in Your Healthcare Journey

Don’t leave your genetic health to chance. The cKIT Mutation Screening provides critical information that can significantly impact your treatment decisions and long-term outcomes. Our experienced team is ready to guide you through the testing process and help you understand what your results mean for your health.

Call us today at +1(267) 388-9828 to schedule your appointment or speak with our genetic counseling team. Take control of your health with comprehensive genetic testing from General Genetics Corporation.

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