Chromosome 11p15 Gene Silver-Russell Syndrome NGS Genetic DNA Test
Comprehensive Genetic Testing for Growth Disorders
The Chromosome 11p15 Silver-Russell Syndrome NGS Genetic DNA Test represents a breakthrough in pediatric genetic diagnostics, offering precise detection of genetic abnormalities associated with Silver-Russell syndrome. This sophisticated test utilizes next-generation sequencing technology to examine the critical 11p15 chromosomal region, which plays a vital role in regulating fetal and childhood growth patterns.
What Does This Test Detect?
This advanced genetic test specifically targets and analyzes:
- Epigenetic alterations in the 11p15 imprinted region
- Methylation abnormalities affecting H19 and IGF2 genes
- Genetic mutations disrupting normal growth regulation
- Chromosomal abnormalities within the 11p15 locus
- Imprinting center defects that impact fetal development
Who Should Consider This Test?
This genetic test is recommended for children and individuals displaying the following clinical features:
Primary Symptoms and Indicators
- Intrauterine growth restriction (IUGR) with birth weight below the 10th percentile
- Postnatal growth failure and failure to thrive
- Characteristic triangular facial features with prominent forehead
- Body asymmetry or hemihypotrophy
- Feeding difficulties during infancy
- Relative macrocephaly at birth
- Clinodactyly of the fifth fingers
- Hypoglycemia in neonatal period
Clinical Scenarios Warranting Testing
- Children with unexplained short stature and growth delays
- Patients with suspected genetic growth disorders
- Families with history of Silver-Russell syndrome
- Cases where conventional growth hormone testing is inconclusive
Benefits of Chromosome 11p15 Genetic Testing
Accurate Diagnosis and Management
Early and precise diagnosis through this test enables healthcare providers to:
- Establish definitive diagnosis of Silver-Russell syndrome
- Develop personalized growth management strategies
- Implement appropriate nutritional interventions
- Monitor and manage associated health complications
- Provide accurate genetic counseling for families
Long-term Health Advantages
- Early intervention for optimal growth outcomes
- Prevention of developmental complications
- Improved quality of life through targeted therapies
- Family planning guidance based on genetic findings
- Comprehensive understanding of the condition’s progression
Understanding Your Test Results
Interpretation Guidelines
Your test results will provide detailed information about:
- Normal Results: No detectable abnormalities in the 11p15 region, suggesting alternative causes for symptoms
- Abnormal Methylation Patterns: Indicates epigenetic alterations consistent with Silver-Russell syndrome
- Genetic Mutations: Specific DNA sequence changes affecting growth regulation
- Complex Findings: May require additional genetic counseling and testing
Next Steps After Testing
- Schedule follow-up consultation with genetic specialist
- Discuss treatment options and management strategies
- Consider implications for family members
- Develop comprehensive care plan with pediatric team
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | Chromosome 11p15 Gene Silver-Russell Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history of the patient
- Genetic counseling session to create family pedigree chart
- Documentation of affected family members with similar conditions
- Review of previous growth and development assessments
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art genetic testing facilities ensure consistent, reliable results regardless of your location.
Take the Next Step Toward Diagnosis
If you suspect Silver-Russell syndrome or have concerns about your child’s growth patterns, our Chromosome 11p15 Genetic DNA Test provides the answers you need. With advanced NGS technology and expert genetic analysis, we deliver comprehensive insights to guide treatment decisions and improve patient outcomes.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take control of your genetic health with precise, reliable testing from America’s leading genetics corporation.
