BLNK Gene Agammaglobulinemia Type 4 Autosomal Recessive NGS Genetic DNA Test
Comprehensive Genetic Testing for Immune System Disorders
The BLNK Gene Agammaglobulinemia Type 4 Autosomal Recessive NGS Genetic DNA Test represents a breakthrough in diagnostic precision for individuals affected by primary immunodeficiency disorders. This advanced genetic analysis specifically targets mutations in the BLNK (B-cell linker) gene, which plays a critical role in B-cell development and antibody production. When this gene malfunctions due to autosomal recessive inheritance patterns, it leads to agammaglobulinemia type 4—a severe condition characterized by significantly reduced or absent antibody levels, leaving patients vulnerable to recurrent and potentially life-threatening infections.
What This Revolutionary Test Detects
Our state-of-the-art NGS (Next-Generation Sequencing) technology meticulously examines the entire BLNK gene sequence to identify:
- Pathogenic variants and mutations in the BLNK gene
- Autosomal recessive inheritance patterns
- Specific genetic alterations affecting B-cell maturation
- Mutations that disrupt pre-B cell receptor signaling
- Genetic markers associated with impaired antibody production
Who Should Consider This Essential Genetic Test
This comprehensive genetic analysis is particularly recommended for individuals experiencing:
- Recurrent bacterial infections starting in infancy or early childhood
- Family history of primary immunodeficiency disorders
- Unexplained failure to thrive in pediatric patients
- Persistent respiratory infections requiring frequent antibiotic treatment
- Delayed or absent B-cell development in laboratory evaluations
- Significantly reduced immunoglobulin levels in blood tests
- Suspected autosomal recessive inheritance patterns of immune deficiency
Significant Benefits of BLNK Gene Testing
Undergoing this precise genetic analysis provides numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Confirms or rules out agammaglobulinemia type 4 with exceptional precision
- Personalized Treatment: Enables targeted therapeutic interventions based on genetic findings
- Family Planning Guidance: Provides crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates prompt initiation of immunoglobulin replacement therapy
- Comprehensive Management: Supports development of individualized infection prevention strategies
- Genetic Risk Assessment: Identifies carrier status in family members for informed decision-making
Understanding Your Test Results
Our comprehensive genetic report provides clear, actionable information:
- Positive Result: Indicates presence of pathogenic BLNK gene mutations confirming agammaglobulinemia type 4 diagnosis
- Negative Result: Suggests absence of detectable BLNK mutations, though clinical correlation remains essential
- Variant of Uncertain Significance: Identifies genetic changes requiring additional clinical interpretation
- Carrier Status: Detects individuals with single mutated BLNK gene copy who may pass the condition to offspring
All results include detailed interpretation by our board-certified genetic specialists and recommendations for appropriate follow-up care.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other cities. Our comprehensive network ensures accessible genetic testing services regardless of your location.
Take Control of Your Health Journey
Don’t let uncertainty about immune system disorders compromise your quality of life. Our BLNK Gene Agammaglobulinemia Type 4 NGS Genetic DNA Test provides the clarity needed for informed medical decisions and personalized treatment approaches. With rapid turnaround times of 3-4 weeks and simple sample collection procedures, obtaining definitive genetic answers has never been more accessible.
Schedule your comprehensive genetic assessment today by calling our dedicated patient care team at +1(267) 388-9828 or book your appointment online through our secure patient portal. Take the first step toward understanding your genetic health and developing an effective management strategy for immune system concerns.
