ABCC2 Gene Dubin-Johnson Syndrome NGS Genetic DNA Test
Comprehensive Genetic Analysis for Liver Function Disorders
The ABCC2 Gene Dubin-Johnson Syndrome NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations associated with Dubin-Johnson syndrome, a rare inherited liver disorder. This comprehensive genetic analysis utilizes next-generation sequencing technology to provide precise detection of abnormalities in the ABCC2 gene, which plays a critical role in bile transport and liver function.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets the ABCC2 gene, which encodes the multidrug resistance-associated protein 2 (MRP2). The test detects:
- Point mutations and single nucleotide variants in the ABCC2 gene
- Insertions and deletions affecting gene function
- Splice site mutations that disrupt protein production
- Copy number variations impacting gene dosage
- Pathogenic variants associated with Dubin-Johnson syndrome
The test employs comprehensive NGS technology that sequences the entire coding region of the ABCC2 gene, ensuring maximum detection sensitivity for clinically relevant mutations.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Persistent or recurrent jaundice without apparent cause
- Elevated conjugated bilirubin levels in blood tests
- Family history of Dubin-Johnson syndrome or similar liver disorders
- Unexplained dark pigmentation of the liver observed during medical imaging
- Chronic mild liver function abnormalities
- Suspected inherited liver transport disorders
- Planning for pregnancy with family history of liver conditions
Clinical Benefits of Genetic Testing
Undergoing the ABCC2 Gene Dubin-Johnson Syndrome NGS Genetic DNA Test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out Dubin-Johnson syndrome with high precision
- Personalized Treatment Planning: Guides appropriate management strategies based on genetic findings
- Family Risk Assessment: Identifies inheritance patterns and assesses risk for family members
- Reproductive Planning: Provides crucial information for family planning decisions
- Differential Diagnosis: Helps distinguish between similar liver disorders
- Long-term Health Monitoring: Establishes baseline for ongoing liver health management
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and medical professionals:
- Positive Result: Indicates the presence of pathogenic mutations in the ABCC2 gene, confirming Dubin-Johnson syndrome diagnosis
- Negative Result: Suggests absence of known disease-causing mutations, though rare variants may still be present
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical implications requiring further evaluation
- Carrier Status: Determines if you carry one copy of a mutated gene, important for family planning
All results include comprehensive genetic counseling to help you understand the implications and next steps for your health management.
Test Information and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | ABCC2 Gene Dubin-Johnson Syndrome NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood |
| Testing Method | Next-Generation Sequencing (NGS) |
| Specialty | Genetics, Hepatology, Endocrinology |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities. Our state-of-the-art laboratories ensure consistent quality and reliable results regardless of your location.
Take Control of Your Genetic Health Today
Don’t let uncertainty about your liver health or family genetic risks affect your quality of life. Our ABCC2 Gene Dubin-Johnson Syndrome NGS Genetic DNA Test provides the clarity and confidence you need for informed healthcare decisions. With our discounted price of $500 USD and comprehensive genetic counseling support, you can access world-class genetic testing without financial burden.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process with compassion and expertise.
