Infliximab Anti-TNF Blocker Test
Understanding Infliximab Therapeutic Drug Monitoring
The Infliximab Anti-TNF Blocker Test represents a critical advancement in personalized medicine for patients undergoing biologic therapy. This sophisticated diagnostic assessment provides essential insights into treatment optimization for individuals receiving infliximab, a monoclonal antibody that targets tumor necrosis factor-alpha (TNF-α). As a cornerstone of modern autoimmune disease management, infliximab has revolutionized treatment approaches for numerous inflammatory conditions, making therapeutic drug monitoring increasingly vital for achieving optimal clinical outcomes.
What Does the Test Measure?
This comprehensive immunoassay evaluates two crucial parameters:
- Infliximab Trough Levels: Measures the concentration of infliximab in the bloodstream just before the next scheduled dose, providing insight into whether therapeutic levels are being maintained
- Anti-Drug Antibodies: Detects the presence of antibodies that the immune system may produce against infliximab, which can neutralize the drug’s effectiveness
Who Should Consider This Test?
This specialized monitoring test is particularly important for patients experiencing:
- Loss of response to infliximab therapy after initial improvement
- Unexpected disease flare-ups despite regular treatment
- Planning for dose optimization or treatment adjustments
- Suspected immunogenicity or antibody development
- Assessment of treatment adherence and effectiveness
Clinical Indications and Symptoms
Patients with the following conditions undergoing infliximab treatment should consider regular monitoring:
- Crohn’s Disease: Persistent abdominal pain, diarrhea, or weight loss
- Ulcerative Colitis: Ongoing rectal bleeding, urgency, or tenesmus
- Rheumatoid Arthritis: Continued joint pain, swelling, or morning stiffness
- Psoriatic Arthritis: Uncontrolled skin lesions or joint inflammation
- Ankylosing Spondylitis: Persistent back pain or spinal stiffness
Benefits of Infliximab Monitoring
Regular therapeutic drug monitoring offers numerous advantages:
- Personalized Treatment Optimization: Enables precise dose adjustments based on individual pharmacokinetics
- Early Detection of Treatment Failure: Identifies subtherapeutic levels or antibody development before clinical symptoms worsen
- Cost-Effective Management: Prevents unnecessary dose escalation and reduces healthcare costs
- Improved Clinical Outcomes: Enhances disease control and quality of life
- Informed Decision Making: Provides objective data for treatment strategy modifications
Understanding Your Test Results
Interpretation Guidelines
Your test results will provide valuable information in several key areas:
Infliximab Trough Levels
- Therapeutic Range (3-7 μg/mL): Indicates adequate drug exposure for most inflammatory conditions
- Subtherapeutic Levels (<3 μg/mL): May suggest need for dose adjustment, increased frequency, or investigation of rapid clearance
- Supratherapeutic Levels (>7 μg/mL): Could indicate potential for dose reduction or increased risk of side effects
Anti-Drug Antibody Status
- Negative: No detectable antibodies, suggesting continued treatment efficacy
- Low Titer: May indicate developing immunogenicity requiring closer monitoring
- High Titer: Suggests significant antibody formation, potentially necessitating treatment modification
Clinical Correlation
It’s essential to interpret these results in the context of your clinical symptoms, disease activity, and overall treatment response. Your gastroenterologist or rheumatologist will integrate this laboratory data with your physical examination findings and symptom assessment to develop the most appropriate management strategy.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Infliximab Anti-TNF Blocker Test | $800 USD | $1000 USD |
Testing Process and Turnaround
Our testing process ensures accuracy and reliability:
- Sample Collection: 3 mL (2 mL minimum) serum from 1 SST tube
- Sampling Timing: Just before your next scheduled dose (trough levels)
- Sample Handling: Ship refrigerated or frozen to maintain sample integrity
- Reporting Timeline: Results available within 2-3 weeks after sample receipt by the 7th of the month
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our extensive network ensures that quality therapeutic drug monitoring is accessible to patients nationwide.
Take Control of Your Treatment Today
Don’t leave your treatment response to chance. The Infliximab Anti-TNF Blocker Test provides the objective data needed to optimize your biologic therapy and achieve the best possible outcomes. Whether you’re experiencing treatment challenges or simply want to ensure your therapy remains effective, this monitoring test offers invaluable insights for you and your healthcare provider.
Ready to Schedule Your Test?
Take the next step toward optimized treatment by calling our dedicated patient care team at +1(267) 388-9828. Our specialists are available to answer your questions, discuss the testing process, and help you schedule your appointment at a convenient location near you. Don’t wait to gain the clarity you need for effective disease management.
Call +1(267) 388-9828 now to book your Infliximab Anti-TNF Blocker Test and take control of your autoimmune disease treatment!
