Immunohistochemistry S100 Test: Advanced Cancer Biomarker Detection
Understanding the Immunohistochemistry S100 Test
The Immunohistochemistry S100 Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect the presence of S100 protein biomarkers in tissue samples. This sophisticated laboratory technique utilizes specialized antibodies that bind specifically to S100 proteins, creating visible markers that pathologists can analyze under microscopy. The S100 protein family plays a critical role in various cellular processes and is particularly abundant in specific cell types, making it an invaluable diagnostic tool for identifying certain cancers and neurological conditions.
What Does the S100 Test Measure?
The Immunohistochemistry S100 Test precisely detects and localizes S100 proteins within tissue specimens. These calcium-binding proteins are primarily found in:
- Melanocytes and melanoma cells
- Schwann cells and nerve sheath tumors
- Glial cells and astrocytomas
- Chondrocytes and cartilage tumors
- Langerhans cells and histiocytosis
Clinical Applications and Who Should Consider This Test
Primary Indications
The Immunohistochemistry S100 Test is essential for patients presenting with:
- Suspicious skin lesions or moles with potential melanoma characteristics
- Neurological symptoms suggesting nerve sheath tumors
- Soft tissue masses requiring precise histological classification
- Metastatic cancer of unknown primary origin
- Follow-up monitoring of previously diagnosed S100-positive tumors
Key Patient Groups
This test is particularly recommended for individuals with:
- Changing or atypical skin lesions
- Family history of melanoma or neurocutaneous syndromes
- Unexplained neurological symptoms
- Previous diagnosis requiring confirmation or staging
- Monitoring treatment response in S100-positive cancers
Comprehensive Benefits of S100 Testing
Diagnostic Precision
The Immunohistochemistry S100 Test offers unparalleled accuracy in tumor identification and classification. By specifically targeting S100 proteins, this test provides:
- Definitive differentiation between melanoma and other skin cancers
- Precise identification of neural crest-derived tumors
- Accurate staging and grading of malignant lesions
- Reliable detection of metastatic disease
Clinical Decision Support
Healthcare providers benefit from S100 test results through:
- Informed treatment planning and surgical margin determination
- Enhanced prognostic assessment and risk stratification
- Guidance for targeted therapy selection
- Improved monitoring of treatment response
Understanding Your Test Results
Interpretation Guidelines
Your Immunohistochemistry S100 Test results will be interpreted by board-certified pathologists and typically fall into these categories:
Positive S100 Staining
A positive result indicates the presence of S100 proteins in the tested tissue, suggesting:
- Melanoma or melanocytic lesions
- Nerve sheath tumors (schwannomas, neurofibromas)
- Certain types of sarcoma
- Neural tissue malignancies
Negative S100 Staining
A negative result typically excludes S100-positive tumors and may indicate:
- Non-melanocytic skin cancers
- Epithelial-derived malignancies
- Other tumor types not expressing S100 proteins
Clinical Correlation
It’s essential to understand that S100 test results must be interpreted in the context of:
- Clinical presentation and patient history
- Other pathological findings
- Additional immunohistochemical markers
- Radiological and laboratory data
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $76 |
| Regular Price | $112 |
Turnaround Time
Our laboratory maintains efficient processing with the following turnaround times:
- Blocks: 5 days
- Tissue Biopsy: 5 days
- Tissue Large Complex: 7 days
- Sample Acceptance: Daily by 6 PM
Sample Requirements and Preparation
Sample Collection
For accurate S100 testing, please submit:
- Tumor tissue preserved in 10% formal-saline solution
- Formalin-fixed paraffin-embedded tissue blocks
- Samples shipped at room temperature
Required Documentation
To ensure proper test interpretation, include:
- Complete histopathology report
- Specific biopsy site information
- Detailed clinical history
- Relevant patient demographics
Nationwide Accessibility
GGC DNA provides comprehensive Immunohistochemistry S100 testing services across the United States. Our state-of-the-art laboratories and collection centers are conveniently located in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Each facility maintains the highest standards of quality and accuracy, ensuring consistent, reliable results for healthcare providers and patients nationwide.
Take Action for Your Health
Don’t delay critical diagnostic information. The Immunohistochemistry S100 Test provides essential data for accurate cancer diagnosis and treatment planning. Our team of experienced oncologists and pathologists is ready to assist you with comprehensive testing and expert interpretation.
Book your Immunohistochemistry S100 Test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take the first step toward precise diagnosis and effective treatment planning with GGC DNA’s advanced cancer biomarker testing services.
