Immunohistochemistry MUC5AC Test
Comprehensive Introduction to MUC5AC Immunohistochemistry Testing
The Immunohistochemistry MUC5AC Test represents a cutting-edge diagnostic approach in modern pathology and oncology. This specialized laboratory procedure utilizes advanced immunohistochemical techniques to detect and visualize the MUC5AC mucin protein within tissue samples. MUC5AC is a crucial glycoprotein primarily expressed in the epithelial cells of the gastrointestinal tract, respiratory system, and various glandular tissues. Its detection and quantification provide invaluable insights for cancer diagnosis, classification, and therapeutic decision-making.
Immunohistochemistry (IHC) has revolutionized cancer diagnostics by enabling pathologists to identify specific protein markers within tissue specimens. The MUC5AC test specifically targets this mucin glycoprotein, which plays significant roles in cellular protection, lubrication, and signaling. When abnormal expression patterns occur, they often indicate underlying pathological conditions, particularly various forms of cancer.
What the Immunohistochemistry MUC5AC Test Measures
This sophisticated diagnostic test specifically detects and quantifies the presence of MUC5AC mucin protein in tissue specimens. The test measures:
- MUC5AC Protein Expression: Identifies the presence and distribution of MUC5AC mucin within tissue samples
- Expression Patterns: Analyzes the cellular localization and intensity of MUC5AC staining
- Tissue Distribution: Maps the specific areas within tissue samples where MUC5AC is expressed
- Quantitative Assessment: Provides semi-quantitative evaluation of staining intensity for diagnostic interpretation
The test utilizes specific antibodies that bind exclusively to MUC5AC antigens, creating visible staining patterns that pathologists can interpret under microscopic examination.
Who Should Consider the MUC5AC Immunohistochemistry Test
This advanced diagnostic test is particularly valuable for individuals presenting with:
Clinical Indications and Symptoms
- Patients with suspected gastrointestinal cancers, including gastric and colorectal malignancies
- Individuals with pancreatic mass lesions or suspected pancreatic adenocarcinoma
- Patients with biliary tract disorders or suspected cholangiocarcinoma
- Cases of mucinous neoplasms requiring precise classification
- Patients with metastatic cancer of unknown primary origin
- Individuals requiring differential diagnosis between various adenocarcinoma subtypes
Specific Clinical Scenarios
- Evaluation of biopsy specimens from gastrointestinal lesions
- Characterization of pancreatic masses and cystic lesions
- Assessment of metastatic deposits to determine tissue of origin
- Monitoring treatment response in mucin-producing tumors
- Prognostic evaluation in certain cancer types
Significant Benefits of MUC5AC Testing
Undergoing the Immunohistochemistry MUC5AC Test provides numerous clinical advantages:
Diagnostic Precision
- Accurate Cancer Classification: Helps distinguish between different types of adenocarcinomas
- Primary Site Identification: Assists in determining the origin of metastatic tumors
- Prognostic Information: Provides valuable data for predicting disease outcomes
- Therapeutic Guidance: Informs treatment selection and management strategies
Clinical Management Advantages
- Personalized Treatment Plans: Enables tailored therapeutic approaches based on specific biomarker expression
- Monitoring Capabilities: Facilitates assessment of treatment response and disease progression
- Comprehensive Evaluation: Complements other diagnostic modalities for complete patient assessment
- Early Intervention Opportunities: Supports timely diagnosis and appropriate management
Understanding Your Test Results
Interpreting MUC5AC immunohistochemistry results requires professional medical expertise, but general guidance includes:
Result Interpretation Framework
- Positive Staining: Indicates presence of MUC5AC expression, commonly seen in gastrointestinal and pancreatic cancers
- Negative Staining: Suggests absence of MUC5AC expression, which may help rule out certain cancer types
- Staining Intensity: The strength of staining can provide additional diagnostic and prognostic information
- Pattern Analysis: The distribution and localization of staining within tissue architecture
Clinical Correlation
Results must always be interpreted in the context of:
- Clinical presentation and patient history
- Other laboratory findings and imaging studies
- Concurrent pathological evaluations
- Overall clinical picture and diagnostic considerations
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $112 |
Turnaround Time
- Sample Acceptance: Daily by 6 PM
- Standard Tissue Block: 5 days
- Tissue Biopsy: 5 days
- Large Complex Tissue: 7 days
Sample Requirements
Submit tumor tissue in 10% formal-saline OR formalin fixed paraffin embedded block. Ship at room temperature. Essential documentation includes:
- Copy of Histopathology report
- Site of biopsy information
- Complete clinical history
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures timely sample processing and reliable result delivery regardless of your location.
Take Action for Your Health
Don’t delay essential diagnostic testing. The Immunohistochemistry MUC5AC Test provides critical information for accurate cancer diagnosis and management. Our experienced team of pathologists and laboratory professionals ensures the highest standards of accuracy and reliability.
Ready to schedule your test? Contact our dedicated patient care team today to discuss your testing needs, obtain pricing information, and schedule your appointment. Call us at +1(267) 388-9828 or reach out via WhatsApp for immediate assistance.
Take the first step toward comprehensive cancer diagnosis and personalized treatment planning with GGC DNA’s advanced Immunohistochemistry MUC5AC testing services.
