HLA Narcolepsy DRB115 DQB10602 DQA10102 Test
Comprehensive Genetic Testing for Narcolepsy Diagnosis
The HLA Narcolepsy DRB115 DQB10602 DQA10102 Test represents a breakthrough in sleep disorder diagnostics, offering precise genetic analysis for individuals suspected of having narcolepsy with cataplexy. This specialized test examines specific human leukocyte antigen (HLA) markers that have been scientifically proven to have a strong association with narcolepsy, providing clinicians with valuable diagnostic information to guide treatment decisions.
What This Advanced Test Measures
Our sophisticated genetic analysis specifically targets three critical HLA alleles:
- HLA-DRB1*15:01 – A primary genetic marker strongly linked to narcolepsy susceptibility
- HLA-DQB1*06:02 – The most significant genetic risk factor for narcolepsy with cataplexy
- HLA-DQA1*01:02 – An essential component of the HLA-DQ heterodimer associated with narcolepsy
Using advanced Sequencing Based Typing (SBT) methodology, our laboratory provides high-resolution genotyping with exceptional accuracy and reliability. This technology enables precise identification of these specific HLA variants, which are present in approximately 95-98% of patients diagnosed with narcolepsy with cataplexy.
Who Should Consider This Genetic Assessment
This specialized test is particularly valuable for individuals experiencing:
- Excessive daytime sleepiness that interferes with daily activities
- Sudden muscle weakness (cataplexy) triggered by strong emotions
- Sleep paralysis episodes upon waking or falling asleep
- Hypnagogic hallucinations – vivid dream-like experiences at sleep onset
- Disrupted nighttime sleep with frequent awakenings
- Automatic behaviors where routine tasks are performed without conscious awareness
If you have a family history of narcolepsy or other sleep disorders, this genetic test can provide important insights into your potential risk factors and help guide appropriate diagnostic evaluation.
Significant Benefits of Genetic Narcolepsy Testing
Choosing our HLA narcolepsy testing offers multiple advantages:
- Early and Accurate Diagnosis: Genetic markers can help confirm narcolepsy diagnosis, especially in complex cases
- Personalized Treatment Planning: Results assist neurologists in developing targeted therapeutic approaches
- Family Risk Assessment: Understanding genetic predisposition helps assess risk for family members
- Reduced Diagnostic Uncertainty: Genetic confirmation can shorten the diagnostic journey
- Comprehensive Sleep Disorder Evaluation: Integrates with other diagnostic tests for complete assessment
Understanding Your Test Results
Our comprehensive report provides clear interpretation of your genetic findings:
- Positive Result: Presence of HLA-DQB1*06:02 and associated alleles indicates increased genetic susceptibility to narcolepsy with cataplexy. This result supports clinical diagnosis but should be interpreted in conjunction with symptoms and other diagnostic tests.
- Negative Result: Absence of these specific HLA markers significantly reduces the likelihood of narcolepsy with cataplexy, though other forms of narcolepsy or sleep disorders may still be present.
- Clinical Correlation: All results should be discussed with your healthcare provider, who will consider your symptoms, medical history, and additional diagnostic findings.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $212 |
| Regular Price | $300 |
| Turnaround Time | 10-12 days |
| Sample Type | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube |
Important Note: Samples must be shipped refrigerated. DO NOT FREEZE. No special preparation is required before testing.
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take Control of Your Sleep Health Today
If you’re experiencing symptoms that suggest narcolepsy or have concerns about your sleep patterns, our HLA Narcolepsy DRB115 DQB10602 DQA10102 Test provides the genetic insights needed for accurate diagnosis and effective treatment planning. Our experienced team is ready to assist you with convenient testing and comprehensive support throughout the process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or learn more about this advanced genetic testing option. Take the first step toward understanding your sleep health and achieving better quality of life through precise genetic diagnosis.