HLA B22 Test – Comprehensive Genetic Analysis for Autoimmune Conditions
Understanding the HLA B22 Test
The HLA B22 Test represents a cutting-edge genetic analysis that examines the HLA-B22 antigen, a critical component of the human leukocyte antigen (HLA) system. This sophisticated testing methodology provides invaluable insights into your immune system’s genetic blueprint and its potential implications for various health conditions.
What is HLA-B22?
HLA-B22 is a specific antigen within the HLA-B locus, which plays a fundamental role in immune system regulation and antigen presentation. This genetic marker is part of the major histocompatibility complex (MHC) located on chromosome 6, serving as a crucial identifier for immune system compatibility and disease susceptibility.
What the HLA B22 Test Measures
Our advanced HLA B22 Test utilizes state-of-the-art Reverse Sequence-Specific Oligonucleotide Probe (Reverse SSOP) technology combined with Luminex detection systems to precisely identify and characterize the HLA-B22 antigen. The test specifically detects:
- Presence or absence of HLA-B22 antigen
- Specific HLA-B22 subtypes and variants
- Genetic markers associated with autoimmune disease susceptibility
- Immune system compatibility markers for transplant considerations
Who Should Consider HLA B22 Testing
Clinical Indications and Symptoms
This test is particularly recommended for individuals experiencing:
- Unexplained autoimmune symptoms including joint pain and inflammation
- Family history of autoimmune disorders such as rheumatoid arthritis or ankylosing spondylitis
- Recurrent inflammatory conditions without clear diagnosis
- Patients being evaluated for organ or bone marrow transplantation
- Individuals with suspected HLA-associated inflammatory diseases
- Those with unexplained chronic fatigue and systemic inflammation
Specialist Recommendations
The HLA B22 Test is commonly ordered by:
- Rheumatologists for autoimmune disease evaluation
- Gastroenterologists for inflammatory bowel disease assessment
- Transplant physicians for compatibility screening
- Immunologists for comprehensive immune system analysis
Benefits of HLA B22 Testing
Early Detection and Prevention
Understanding your HLA-B22 status provides numerous advantages:
- Early Risk Identification: Detect genetic predispositions before symptoms manifest
- Personalized Treatment Planning: Guide therapeutic approaches based on genetic profile
- Transplant Compatibility Assessment: Critical for successful organ and bone marrow transplantation
- Family Planning Insights: Understand potential hereditary risks for future generations
- Comprehensive Health Management: Integrate genetic information into overall wellness strategies
Understanding Your Test Results
Interpreting HLA B22 Findings
Your test results will provide detailed information about your HLA-B22 status:
- Positive for HLA-B22: Indicates presence of the antigen, which may be associated with specific autoimmune conditions or transplant compatibility considerations
- Negative for HLA-B22: Absence of this specific antigen, which may influence disease risk profiles and treatment options
- Specific Subtype Identification: Detailed characterization of HLA-B22 variants for precise medical interpretation
Clinical Correlation
It’s essential to understand that HLA testing provides genetic information that must be interpreted in the context of your complete medical picture. Our genetic counselors and healthcare providers will help you understand how these results relate to your specific health situation and guide appropriate next steps.
Test Details and Pricing
| Test Information | Details |
|---|---|
| Test Name | HLA B22 Test |
| Regular Price | $212 USD |
| Discount Price | $150 USD |
| Turnaround Time | 10-12 days |
| Sample Type | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube |
| Testing Method | Reverse SSOP – Luminex |
| Preparation | No special preparation required |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible testing wherever you are located.
Take Control of Your Genetic Health
Understanding your HLA-B22 status can provide crucial insights into your immune system’s genetic makeup and potential health risks. With our advanced testing technology and expert interpretation, you gain valuable information to guide your healthcare decisions and preventive strategies.
Ready to Schedule Your Test?
Take the first step toward comprehensive genetic understanding. Our team of genetic specialists and healthcare professionals is ready to assist you with scheduling, questions, and result interpretation.
Call or WhatsApp us today at +1(267) 388-9828 to book your HLA B22 Test appointment.
Don’t wait to gain valuable insights into your genetic health profile. Our convenient testing process, competitive pricing at only $150, and nationwide availability make comprehensive genetic testing accessible to everyone seeking to understand their unique genetic makeup and potential health risks.

