FISH PDGFR Alpha 4q12 Gene Rearrangement Test
Comprehensive Genetic Analysis for Leukemia Diagnosis
The FISH PDGFR Alpha 4q12 Gene Rearrangement Test represents a cutting-edge diagnostic approach in modern hematology and oncology. This specialized fluorescence in situ hybridization (FISH) test specifically targets the platelet-derived growth factor receptor alpha (PDGFR Alpha) gene located on chromosome 4q12, providing critical information for the accurate diagnosis and management of various hematologic malignancies.
What This Advanced Genetic Test Detects
The FISH PDGFR Alpha 4q12 Gene Rearrangement Test identifies specific chromosomal abnormalities involving the PDGFR Alpha gene, which plays a crucial role in cell growth and division regulation. When this gene undergoes rearrangement, it can lead to uncontrolled cell proliferation characteristic of certain leukemias and myeloid neoplasms.
- Detection of PDGFR Alpha gene fusion events
- Identification of specific chromosomal translocations
- Assessment of gene amplification or deletion
- Confirmation of eosinophilic leukemia markers
- Evaluation of treatment-responsive genetic alterations
Who Should Consider This Genetic Test?
This specialized genetic analysis is recommended for patients presenting with specific clinical indications that suggest underlying hematologic disorders.
Clinical Indications and Symptoms
- Patients with unexplained eosinophilia or hypereosinophilic syndrome
- Individuals diagnosed with chronic eosinophilic leukemia
- Cases of suspected myeloid/lymphoid neoplasms with eosinophilia
- Patients with atypical myeloproliferative disorders
- Individuals requiring targeted therapy selection for hematologic malignancies
- Patients with treatment-resistant leukemia requiring alternative therapeutic options
Significant Benefits of Genetic Testing
Undergoing the FISH PDGFR Alpha 4q12 Gene Rearrangement Test provides numerous advantages for both patients and healthcare providers in managing hematologic conditions.
Key Advantages
- Accurate Diagnosis: Provides definitive identification of specific genetic abnormalities
- Targeted Treatment: Enables selection of appropriate tyrosine kinase inhibitors
- Prognostic Information: Offers insights into disease progression and treatment response
- Personalized Medicine: Supports development of individualized treatment plans
- Monitoring Capability: Allows tracking of treatment effectiveness over time
- Early Intervention: Facilitates timely therapeutic decisions for improved outcomes
Understanding Your Test Results
Interpreting the results of the FISH PDGFR Alpha 4q12 Gene Rearrangement Test requires specialized expertise, but understanding the general implications can help patients and families navigate their healthcare journey.
Result Interpretation Guidelines
- Positive Result: Indicates presence of PDGFR Alpha gene rearrangement, suggesting specific types of leukemia that may respond to targeted therapies
- Negative Result: Suggests absence of the tested genetic abnormalities, helping to rule out certain leukemia subtypes
- Consultation Required: All results should be discussed with your hematologist or oncologist for proper interpretation and treatment planning
- Clinical Correlation: Results must be considered alongside other diagnostic findings and clinical presentation
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $150 |
| Regular Price | $212 |
Testing Process Details
- Turnaround Time: Sample accepted daily by 4 pm; Results in 4 working days
- Sample Requirements: 5 mL (3 mL minimum) whole blood OR 4 mL (2 mL minimum) Bone Marrow from 2 Green Top (Sodium Heparin) tubes
- Shipping Instructions: Ship at 18-22°C. DO NOT FREEZE
- Required Documentation: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory
Nationwide Testing Availability
We have branches across the United States, making advanced genetic testing accessible to patients in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our nationwide network ensures that patients receive consistent, high-quality genetic testing services regardless of location.
Take Control of Your Health Today
Don’t wait to get the critical genetic information you need for accurate diagnosis and effective treatment planning. Our experienced team of genetic specialists and advanced testing facilities are ready to provide you with comprehensive genetic analysis and support.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your FISH PDGFR Alpha 4q12 Gene Rearrangement Test and take the first step toward personalized cancer care.
Our dedicated genetic counselors and healthcare professionals are available to answer your questions, explain the testing process, and help you understand how this advanced genetic analysis can benefit your specific health situation. Early and accurate genetic testing can make a significant difference in treatment outcomes and quality of life.
