Estradiol Ultrasensitive Test: Precision Hormone Analysis
Understanding the Estradiol Ultrasensitive Test
The Estradiol Ultrasensitive Test represents a breakthrough in endocrine diagnostics, offering unprecedented precision in measuring estradiol levels. Estradiol, the most potent form of estrogen, plays a critical role in numerous bodily functions including reproductive health, bone density maintenance, cardiovascular protection, and cognitive function. Traditional estradiol tests often lack the sensitivity required to detect subtle hormonal fluctuations, particularly in postmenopausal women, men, and individuals undergoing specific medical treatments. This ultrasensitive version utilizes cutting-edge LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) technology to provide accurate measurements even at extremely low concentrations.
What This Test Measures
The Estradiol Ultrasensitive Test specifically quantifies:
- Ultra-low concentrations of estradiol (E2) in serum
- Precise hormone levels down to 1-2 pg/mL
- Subtle hormonal fluctuations that standard tests miss
- Baseline estrogen levels for comprehensive endocrine assessment
Who Should Consider This Test?
This specialized testing is particularly beneficial for individuals experiencing:
- Fertility Concerns: Women undergoing fertility treatments, IVF cycles, or ovulation induction
- Menopausal Symptoms: Women transitioning through perimenopause and menopause
- Hormone Replacement Therapy: Patients receiving HRT who require precise monitoring
- Reproductive Disorders: Individuals with polycystic ovary syndrome (PCOS), endometriosis, or irregular menstrual cycles
- Male Hormone Issues: Men with gynecomastia, low libido, or suspected estrogen imbalances
- Pediatric Endocrinology: Children with precocious or delayed puberty
- Cancer Patients: Individuals receiving aromatase inhibitor therapy for breast cancer
Key Benefits of Ultrasensitive Testing
Unmatched Precision and Accuracy
The LC-MS/MS methodology employed in this test eliminates cross-reactivity with other estrogen metabolites, providing results that are significantly more accurate than conventional immunoassays. This precision is crucial for:
- Optimizing hormone replacement therapy dosages
- Monitoring aromatase inhibitor effectiveness
- Assessing ovarian reserve in fertility patients
- Evaluating hypothalamic-pituitary-gonadal axis function
Clinical Applications
This test offers valuable insights for:
- Reproductive Endocrinology: Comprehensive evaluation of ovarian function and menstrual cycle disorders
- Menopause Management: Accurate assessment of menopausal status and treatment efficacy
- Pediatric Development: Monitoring pubertal development and identifying endocrine abnormalities
- Oncology Care: Monitoring estrogen suppression in hormone-sensitive cancers
Understanding Your Test Results
Interpreting Estradiol Ultrasensitive Test results requires consideration of several factors:
Reference Ranges
- Premenopausal Women: Levels vary throughout menstrual cycle (typically 30-400 pg/mL)
- Postmenopausal Women: Generally below 20 pg/mL
- Men: Typically 10-40 pg/mL
- Children: Age and Tanner stage dependent
Clinical Interpretation
Your healthcare provider will consider:
- Your age, gender, and clinical symptoms
- Menstrual cycle timing for premenopausal women
- Current medications and treatments
- Correlation with other hormone levels
- Clinical context and medical history
When to Consult Your Doctor
Discuss your results with your healthcare provider if you notice:
- Unexpectedly high or low values
- Results inconsistent with your symptoms
- Need for treatment adjustments
- Concerns about fertility or reproductive health
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Estradiol Ultrasensitive Test | $74 USD | $82 USD |
Testing Process and Turnaround
- Sample Collection: Simple blood draw (2 mL serum minimum)
- Collection Days: Monday and Thursday by 9:00 AM
- Report Availability: Wednesday and Saturday
- Sample Requirements: Red Top tube (no additive), avoid SST gel barrier tubes
- Shipping: Refrigerated or frozen transport
- Preparation: No special preparation required
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including:
- New York City and surrounding tri-state area
- Los Angeles and Southern California region
- Chicago and Midwest locations
- Houston, Dallas, and Texas facilities
- Miami, Orlando, and Florida centers
- Phoenix, Las Vegas, and Southwest clinics
- Seattle, Portland, and Pacific Northwest offices
- Boston, Philadelphia, and Northeast locations
Take Control of Your Hormonal Health Today
Don’t let hormonal imbalances affect your quality of life. The Estradiol Ultrasensitive Test provides the precise data needed for informed healthcare decisions. Our advanced LC-MS/MS technology ensures results you can trust, while our nationwide network makes testing convenient and accessible.
Ready to schedule your test? Contact our dedicated patient care team today to book your appointment or discuss your testing needs. Call or WhatsApp us at +1(267) 388-9828 for immediate assistance and personalized service.
Take the first step toward optimal hormonal health with the most accurate estradiol testing available. Our team of endocrine specialists and genetic counselors are ready to support your journey to better health.

