Familial Mediterranean Fever MEFV Full Gene Analysis
Comprehensive Genetic Testing for Familial Mediterranean Fever
Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder characterized by recurrent episodes of fever and inflammation in the abdomen, chest, and joints. The MEFV Full Gene Analysis represents a cutting-edge diagnostic approach that examines the complete MEFV gene using Next-Generation Sequencing (NGS) technology. This comprehensive test provides crucial insights for individuals experiencing unexplained recurrent inflammatory episodes and helps establish accurate diagnosis for proper treatment planning.
What Does the MEFV Full Gene Analysis Test Measure?
This advanced genetic test performs complete sequencing of the MEFV gene to identify mutations associated with Familial Mediterranean Fever. The analysis covers:
- Full gene sequencing of all MEFV exons and intron-exon boundaries
- Detection of known pathogenic variants including M694V, V726A, M680I, and M694I
- Identification of novel mutations that may contribute to FMF symptoms
- Comprehensive variant analysis with clinical correlation
Who Should Consider This Genetic Test?
This test is recommended for individuals experiencing:
- Recurrent unexplained fevers lasting 1-3 days
- Severe abdominal pain mimicking appendicitis
- Chest pain due to pleuritis or pericarditis
- Joint inflammation and arthritis symptoms
- Skin rashes, particularly erysipelas-like erythema
- Family history of similar symptoms or FMF diagnosis
- Mediterranean, Middle Eastern, or Jewish ancestry with recurrent inflammatory symptoms
Key Benefits of MEFV Genetic Testing
Undergoing MEFV Full Gene Analysis provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out FMF with high precision
- Early Intervention: Enables timely treatment with colchicine to prevent amyloidosis
- Family Planning: Provides genetic counseling information for family members
- Treatment Guidance: Helps physicians tailor appropriate therapeutic strategies
- Symptom Management: Reduces frequency and severity of inflammatory attacks
- Prevention of Complications: Minimizes risk of kidney damage and other long-term effects
Understanding Your Test Results
Your MEFV Full Gene Analysis results will be carefully interpreted by our genetic specialists:
- Positive Result: Indicates presence of pathogenic MEFV mutations consistent with FMF diagnosis
- Negative Result: Suggests FMF is unlikely, though clinical correlation is essential
- Variant of Uncertain Significance: Requires additional clinical evaluation and family studies
- Carrier Status: Identifies individuals with single mutation who may pass FMF to offspring
All results include detailed interpretation and recommendations for follow-up care with your healthcare provider.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | Familial Mediterranean Fever MEFV Full Gene Analysis |
| Discount Price | $900 USD |
| Regular Price | $1200 USD |
| Turnaround Time | 4-6 weeks |
| Sample Type | Peripheral blood |
| Test Components | EDTA Vacutainer (3 ml) |
| Testing Method | Next-Generation Sequencing (NGS) |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York City, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible genetic testing services for patients throughout the country.
Take Control of Your Health Today
Don’t let unexplained symptoms control your life. The MEFV Full Gene Analysis provides definitive answers about Familial Mediterranean Fever, enabling proper diagnosis and effective treatment. Our genetic counselors and medical specialists are available to discuss your results and provide comprehensive support throughout your diagnostic journey.
Book your Familial Mediterranean Fever MEFV Full Gene Analysis today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take the first step toward understanding your genetic health and managing recurrent inflammatory symptoms effectively.
