CLCNKB Gene Bartter Syndrome Type 3 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Inherited Kidney Disorders
The CLCNKB Gene Bartter Syndrome Type 3 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations associated with Bartter syndrome type 3, a rare inherited kidney disorder. This sophisticated genetic analysis provides crucial insights into the underlying causes of electrolyte imbalances and renal tubular dysfunction, enabling healthcare providers to deliver targeted, personalized care for affected individuals and their families.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets the CLCNKB gene, which encodes the chloride channel protein ClC-Kb essential for proper kidney function. The test utilizes Next-Generation Sequencing (NGS) technology to comprehensively analyze the entire CLCNKB gene sequence, identifying:
- Point mutations affecting chloride channel function
- Insertion and deletion variants disrupting protein structure
- Splice site mutations altering gene expression
- Novel genetic variants associated with renal salt-wasting
- Inheritance patterns for family genetic counseling
Who Should Consider This Genetic Test?
This specialized genetic analysis is recommended for individuals presenting with clinical symptoms suggestive of Bartter syndrome type 3, including:
- Excessive urination (polyuria) and thirst (polydipsia)
- Persistent salt cravings and electrolyte imbalances
- Muscle weakness, cramps, or tetany
- Growth retardation in children and adolescents
- Low blood potassium levels (hypokalemia)
- Metabolic alkalosis with normal blood pressure
- Family history of kidney disorders or electrolyte abnormalities
- Unexplained renal tubular dysfunction
Key Benefits of Genetic Testing
Undergoing the CLCNKB Gene Bartter Syndrome Type 3 NGS Genetic DNA Test offers numerous advantages for patients and healthcare providers:
- Accurate Diagnosis: Provides definitive genetic confirmation of Bartter syndrome type 3, eliminating diagnostic uncertainty
- Personalized Treatment: Enables targeted therapeutic interventions based on specific genetic findings
- Family Planning: Offers valuable information for genetic counseling and reproductive decision-making
- Early Intervention: Facilitates timely management to prevent complications and improve long-term outcomes
- Comprehensive Analysis: NGS technology ensures thorough examination of the entire CLCNKB gene
Understanding Your Test Results
Our comprehensive genetic report provides detailed interpretation of your CLCNKB gene analysis:
- Positive Result: Identifies pathogenic mutations confirming Bartter syndrome type 3 diagnosis
- Negative Result: No disease-causing variants detected in the CLCNKB gene
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation
- Carrier Status: Determines if individuals carry one copy of a mutated gene
All results include detailed clinical implications and recommendations for follow-up care. Our genetic counseling team provides comprehensive support to help you understand your results and make informed healthcare decisions.
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | CLCNKB Gene Bartter Syndrome Type 3 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States, with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible testing for patients nationwide.
Take Control of Your Genetic Health Today
Don’t let uncertainty about inherited kidney disorders affect your quality of life. The CLCNKB Gene Bartter Syndrome Type 3 NGS Genetic DNA Test provides the clarity and confidence you need for informed healthcare decisions. Our experienced genetic counselors and medical professionals are ready to support you through every step of the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic consultation and testing appointment. Take the first step toward understanding your genetic health and securing personalized medical care tailored to your specific needs.
