Y Chromosome Microdeletion 16 Mutations Test
Understanding Y Chromosome Microdeletions
Y Chromosome Microdeletion testing represents a crucial advancement in male reproductive medicine, providing essential insights into genetic factors contributing to infertility. The Y chromosome contains specific regions known as azoospermia factor (AZF) regions that house genes critical for normal sperm production and development. When microdeletions occur in these regions, they can significantly impair male fertility by disrupting the complex process of spermatogenesis.
What This Test Measures
The Y Chromosome Microdeletion 16 Mutations Test utilizes sophisticated Multiplex End Point PCR technology to examine 16 specific genetic markers across three primary AZF regions:
- AZFa Region: Contains genes essential for early sperm development
- AZFb Region: Critical for sperm maturation and progression
- AZFc Region: Most commonly affected region, associated with varying degrees of spermatogenic failure
Who Should Consider This Test?
This genetic screening is particularly important for men experiencing:
- Unexplained infertility despite normal hormone levels
- Severe oligospermia (low sperm count)
- Non-obstructive azoospermia (absence of sperm in semen)
- Family history of male infertility
- Planning assisted reproductive technologies
- Previous unsuccessful fertility treatments
Clinical Indications and Symptoms
Men presenting with the following clinical scenarios should strongly consider Y chromosome microdeletion testing:
- Persistent infertility lasting more than one year
- Abnormal semen analysis results
- Testicular volume reduction
- Elevated FSH levels with normal testosterone
- Planning for testicular sperm extraction procedures
Benefits of Y Chromosome Microdeletion Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Identifies specific genetic causes of male infertility
- Treatment Guidance: Helps determine appropriate fertility interventions
- Genetic Counseling: Provides valuable information for family planning
- Cost-Effective: Avoids unnecessary fertility treatments
- Proactive Health Management: Enables informed reproductive decisions
Understanding Your Test Results
Your Y Chromosome Microdeletion test results will fall into one of several categories:
- Normal Result: No microdeletions detected in the 16 tested regions
- AZFa Deletion: Associated with Sertoli-cell-only syndrome and complete absence of sperm
- AZFb Deletion: Typically results in maturation arrest and absence of mature sperm
- AZFc Deletion: Most common deletion, associated with variable spermatogenic failure
- Combined Deletions: Multiple region involvement indicating more severe genetic impact
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | Y Chromosome Microdeletion 16 Mutations |
| Discount Price | $200 USD |
| Regular Price | $250 USD |
| Turnaround Time | 10 Days |
| Sample Type | Peripheral Blood |
| Test Components | EDTA Vacutainer (2ml) |
| Testing Method | Multiplex End Point PCR |
Pre-Test Instructions
The Y Chromosome Microdeletion (16 Mutations) test requires a Doctor’s prescription for most cases. Please note that prescriptions are not applicable for surgical procedures, pregnancy-related testing, or individuals planning international travel. Our genetic counselors are available to discuss any pre-test requirements and answer your questions.
Nationwide Testing Availability
GGC DNA maintains comprehensive laboratory facilities across the United States, ensuring convenient access to advanced genetic testing services. Our network includes specialized testing centers in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and numerous other locations nationwide.
Book Your Test Today
Take the first step toward understanding your genetic fertility profile. Our experienced genetic counselors and reproductive specialists are ready to assist you with comprehensive testing and personalized guidance.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your Y Chromosome Microdeletion test appointment. Our team will help you understand the testing process, answer your questions, and coordinate with your healthcare provider as needed.
Early genetic assessment can provide critical information for your reproductive health journey. Contact GGC DNA now to book your comprehensive male fertility genetic evaluation.
