XRCC3 Gene Melanoma Cutaneous Malignant Familial Type 6 Susceptibility NGS Genetic DNA Test
Comprehensive Genetic Assessment for Hereditary Melanoma Risk
The XRCC3 Gene Melanoma Susceptibility Test represents a significant advancement in personalized cancer risk assessment. This sophisticated genetic analysis utilizes next-generation sequencing (NGS) technology to evaluate mutations in the XRCC3 gene, which plays a crucial role in DNA repair mechanisms. When this gene contains specific variations, individuals may experience increased susceptibility to cutaneous malignant melanoma, particularly in familial patterns classified as type 6.
What This Test Measures and Detects
This comprehensive genetic analysis specifically targets:
- Comprehensive sequencing of the XRCC3 gene using advanced NGS technology
- Identification of pathogenic variants associated with familial melanoma type 6
- Assessment of DNA repair pathway efficiency and mutation burden
- Evaluation of genetic markers linked to increased melanoma susceptibility
- Detection of both inherited and de novo mutations affecting cancer risk
Who Should Consider This Genetic Test
This test is particularly recommended for individuals with:
- Personal history of multiple primary melanomas
- Family history of melanoma across multiple generations
- Early-onset melanoma diagnosis (before age 50)
- Multiple atypical moles or dysplastic nevi syndrome
- Family members with confirmed XRCC3 gene mutations
- Unexplained familial clustering of skin cancers
- Concerns about hereditary cancer predisposition
Clinical Benefits of Genetic Testing
Undergoing XRCC3 gene testing provides numerous advantages:
- Personalized Risk Assessment: Quantify individual melanoma susceptibility based on genetic profile
- Proactive Surveillance: Implement targeted screening protocols for early detection
- Family Planning: Inform reproductive decisions and family risk assessment
- Preventive Strategies: Develop customized sun protection and lifestyle recommendations
- Treatment Guidance: Inform therapeutic approaches based on genetic markers
- Psychological Relief: Reduce uncertainty through definitive genetic information
Understanding Your Test Results
Your genetic test report will provide detailed information about your XRCC3 gene status:
- Positive Result: Indicates presence of pathogenic mutation, suggesting increased melanoma risk requiring enhanced surveillance
- Negative Result: No detected mutations in XRCC3 gene, though other genetic factors may still contribute to risk
- Variant of Uncertain Significance: Identified genetic change with unknown clinical impact requiring ongoing research
- Carrier Status: Information about inheritance patterns and family implications
All results should be discussed with a qualified genetic counselor or oncologist to develop appropriate management strategies.
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | XRCC3 Gene Melanoma Cutaneous Malignant Familial Type 6 Susceptibility NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We provide comprehensive genetic testing services across the United States with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible testing regardless of your location.
Take Control of Your Genetic Health Today
Understanding your genetic predisposition to melanoma can be life-saving. Early identification of increased risk allows for proactive monitoring and preventive measures that significantly improve outcomes. Our team of genetic specialists and oncology experts are ready to guide you through the testing process and help interpret your results within the context of your personal and family health history.
Ready to schedule your genetic assessment? Contact our genetic counseling team today at +1(267) 388-9828 to discuss your testing options, schedule pre-test genetic counseling, and begin your journey toward personalized cancer risk management.
Don’t wait to gain valuable insights into your genetic health. Book your XRCC3 Gene Melanoma Susceptibility Test now and take the first step toward informed health decisions and proactive cancer prevention strategies.
