WT1 Gene Wilms Tumor Type 1 Familial NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Cancer Risk
The WT1 Gene Wilms Tumor Type 1 Familial NGS Genetic DNA Test represents a cutting-edge approach to identifying genetic predispositions to hereditary cancers and associated conditions. This sophisticated diagnostic tool utilizes next-generation sequencing technology to analyze the WT1 gene, which plays a critical role in kidney development and tumor suppression. Understanding your genetic makeup can provide invaluable insights into your health risks and empower you to make informed medical decisions.
What Does This Test Measure and Detect?
This comprehensive genetic analysis specifically targets the WT1 gene, detecting various types of mutations including:
- Point mutations affecting gene function
- Insertions and deletions disrupting protein structure
- Frameshift mutations altering genetic coding
- Splice site variants affecting RNA processing
- Copy number variations impacting gene dosage
The test employs advanced NGS technology to provide high-resolution analysis of the entire WT1 gene coding region, ensuring comprehensive mutation detection with exceptional accuracy and reliability.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals with:
- Personal history of Wilms tumor or childhood kidney cancers
- Family members diagnosed with Wilms tumor or related renal conditions
- History of Denys-Drash syndrome features including nephropathy and genital abnormalities
- Frasier syndrome characteristics with gonadal dysgenesis
- Multiple family members with kidney disorders or childhood cancers
- Unexplained nephrotic syndrome in childhood
- Associated endocrine abnormalities or genital development issues
Clinical Benefits of WT1 Genetic Testing
Undergoing this genetic analysis provides numerous advantages for patients and their families:
- Early Risk Assessment: Identify genetic predispositions before symptoms develop
- Personalized Surveillance: Implement targeted screening protocols based on genetic findings
- Family Planning Guidance: Make informed reproductive decisions with genetic counseling
- Proactive Management: Develop preventive strategies for at-risk family members
- Treatment Optimization: Guide therapeutic approaches based on genetic profile
- Peace of Mind: Reduce uncertainty through comprehensive genetic understanding
Understanding Your Test Results
Your genetic test results will be thoroughly explained during your genetic counseling session. Possible outcomes include:
- Positive Result: Identification of a pathogenic WT1 mutation indicating increased cancer risk and requiring specialized management
- Negative Result: No detected mutations in the WT1 gene, though other genetic factors may still contribute to risk
- Variant of Uncertain Significance: Identification of genetic changes with unknown clinical significance requiring ongoing monitoring
- Benign Polymorphism: Common genetic variations not associated with increased disease risk
Our genetic counselors will provide personalized interpretation and create a comprehensive management plan based on your specific results and family history.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | WT1 Gene Wilms Tumor Type 1 Familial NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before undergoing testing, patients should provide:
- Complete clinical history including any renal, endocrine, or developmental concerns
- Detailed family medical history with emphasis on cancer patterns
- Participation in genetic counseling to create comprehensive pedigree analysis
- Understanding of test implications and potential outcomes
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and medical professionals ensures consistent, high-quality care regardless of location.
Take Control of Your Genetic Health Today
Understanding your genetic predisposition to hereditary conditions can be life-changing. Our comprehensive WT1 genetic testing provides the clarity and confidence needed to make informed healthcare decisions. With advanced NGS technology, expert genetic counseling, and nationwide accessibility, we make genetic testing accessible and understandable.
Ready to learn more about your genetic health? Contact our genetic specialists today at +1(267) 388-9828 to schedule your consultation and testing appointment. Take the first step toward proactive health management and peace of mind for you and your family.
Note: This test is conducted under the supervision of board-certified genetic counselors and medical geneticists. All testing follows established clinical guidelines and ethical standards for genetic testing.
