WNT7A Gene Ulna and Fibula Absence with Severe Limb Deficiency NGS Genetic DNA Test
Comprehensive Genetic Analysis for Severe Limb Malformations
The WNT7A Gene Ulna and Fibula Absence with Severe Limb Deficiency NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations responsible for severe congenital limb deficiencies. This specialized test focuses on the WNT7A gene, which plays a critical role in embryonic limb development and patterning. When mutations occur in this gene, they can lead to profound skeletal abnormalities including complete absence of the ulna and fibula bones, resulting in significant functional limitations and complex medical challenges.
What This Advanced Genetic Test Measures
Our comprehensive NGS (Next-Generation Sequencing) genetic DNA test specifically targets:
- Complete sequencing of the WNT7A gene to identify pathogenic variants
- Detection of point mutations, insertions, deletions, and copy number variations
- Analysis of genetic markers associated with ulna and fibula absence
- Identification of autosomal recessive inheritance patterns
- Assessment of mutation impact on limb development pathways
Who Should Consider This Genetic Test
This specialized genetic testing is recommended for individuals presenting with:
- Congenital absence of ulna and/or fibula bones
- Severe upper and lower limb deficiencies at birth
- Family history of similar limb malformations
- Unexplained skeletal dysplasias affecting limb development
- Multiple family members with congenital limb abnormalities
- Parents planning pregnancy with known family history of limb deficiencies
Key Benefits of WNT7A Genetic Testing
- Accurate Diagnosis: Provides definitive genetic confirmation of WNT7A-related limb deficiencies
- Family Planning Guidance: Enables informed reproductive decisions for at-risk families
- Personalized Management: Helps develop targeted treatment and rehabilitation strategies
- Genetic Counseling Support: Facilitates comprehensive family risk assessment
- Early Intervention Planning: Allows for proactive medical and surgical planning
- Research Contribution: Advances understanding of limb development genetics
Understanding Your Test Results
Our genetic specialists provide comprehensive interpretation of your WNT7A gene test results:
- Positive Result: Identifies a pathogenic mutation in the WNT7A gene, confirming the genetic basis for limb deficiencies
- Negative Result: No mutation detected in WNT7A gene, suggesting other genetic or environmental factors
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Determines if individuals carry one copy of a mutated gene without showing symptoms
Test Pricing and Availability
| Test Feature | Details |
|---|---|
| Test Name | WNT7A Gene Ulna and Fibula Absence with Severe Limb Deficiency NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee. Our extensive network ensures accessible genetic testing services for families throughout the country.
Take the Next Step Toward Genetic Clarity
If you or your family members are affected by severe limb deficiencies or have concerns about genetic inheritance patterns, our WNT7A genetic test provides the answers you need. Our team of genetic counselors and specialists are ready to guide you through the testing process and help you understand your results.
Book your WNT7A Genetic DNA Test today by calling our dedicated genetic testing line at +1(267) 388-9828 or schedule your appointment online. Take control of your genetic health journey with confidence and clarity.
