WNT7A Gene Fibular Aplasia or Hypoplasia, Femoral Bowing and Polysyndactyly Oligodactyly NGS Genetic DNA Test
Comprehensive Genetic Analysis for Skeletal Dysplasia Conditions
The WNT7A Gene NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying rare genetic disorders affecting skeletal development. This specialized test focuses on the WNT7A gene, which plays a critical role in embryonic limb development and patterning. Mutations in this gene are associated with complex congenital conditions characterized by limb abnormalities and skeletal malformations.
What Does This Test Measure and Detect?
This advanced next-generation sequencing (NGS) test specifically analyzes the WNT7A gene to identify pathogenic variants responsible for:
- Fibular aplasia (complete absence) or hypoplasia (underdevelopment)
- Femoral bowing and abnormalities
- Polysyndactyly (extra fingers or toes with fused digits)
- Oligodactyly (reduced number of fingers or toes)
- Other associated limb development disorders
The test utilizes state-of-the-art NGS technology to provide comprehensive coverage of the entire WNT7A gene, ensuring high detection rates for both common and rare mutations.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals presenting with:
- Newborns or children with congenital limb abnormalities
- Individuals with family history of skeletal dysplasia conditions
- Patients with unexplained femoral bowing or fibular defects
- Those with complex hand and foot malformations including extra or missing digits
- Individuals seeking genetic counseling for family planning purposes
- Patients with suspected WNT7A-related disorders based on clinical presentation
Clinical Benefits of WNT7A Genetic Testing
Undergoing this specialized genetic analysis provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out WNT7A-related disorders with high precision
- Family Planning Guidance: Provides crucial information for genetic counseling and reproductive decisions
- Personalized Management: Enables targeted treatment approaches based on specific genetic findings
- Prognostic Information: Helps predict disease progression and potential complications
- Early Intervention: Facilitates timely orthopedic and rehabilitation interventions
- Research Contribution: Contributes to better understanding of rare skeletal disorders
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert geneticists and presented with comprehensive explanations:
- Positive Result: Indicates the presence of a pathogenic mutation in the WNT7A gene, confirming the genetic basis of the observed symptoms
- Negative Result: Suggests that WNT7A mutations are not responsible for the clinical presentation, guiding further diagnostic evaluation
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: Determines if individuals carry mutations that could be passed to offspring
All results include detailed interpretation and recommendations for next steps, with genetic counseling available to help you understand the implications.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Pre-Test Requirements
Before scheduling your test, please ensure you have:
- Complete clinical history of the patient
- Genetic counseling session to document family pedigree
- Detailed information about affected family members
- Relevant medical records and imaging studies
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States, with convenient locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about skeletal development disorders affect your quality of life. Our specialized WNT7A genetic testing provides the answers you need for informed medical decisions and personalized care planning.
Ready to schedule your test? Contact our genetic specialists today:
Phone: +1(267) 388-9828
WhatsApp: +1(267) 388-9828
Our team of certified genetic counselors and medical professionals is ready to guide you through the testing process and help you understand your results. Book your appointment now and take the first step toward genetic clarity and improved health management.
