WNT4 Gene SERKAL Syndrome NGS Genetic DNA Test
Comprehensive Genetic Analysis for Developmental Disorders
The WNT4 Gene SERKAL Syndrome NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare developmental conditions. This advanced testing methodology provides crucial insights into the genetic basis of SERKAL syndrome, enabling accurate diagnosis and personalized treatment approaches for affected individuals and their families.
What is SERKAL Syndrome?
SERKAL syndrome (Sex Reversal, Kidneys, Adrenal, and Lung dysgenesis) is an extremely rare genetic disorder characterized by complex developmental abnormalities affecting multiple organ systems. The condition results from mutations in the WNT4 gene, which plays a critical role in embryonic development, particularly in the formation of reproductive organs, kidneys, and adrenal glands.
What the Test Measures and Detects
Our comprehensive NGS-based genetic test specifically targets the WNT4 gene to identify pathogenic variants responsible for SERKAL syndrome. The test analyzes:
- Point mutations and small insertions/deletions in the WNT4 gene
- Copy number variations affecting gene function
- Regulatory region abnormalities
- Novel genetic variants with potential clinical significance
Advanced NGS Technology
Utilizing state-of-the-art Next-Generation Sequencing technology, our test provides unparalleled accuracy and comprehensive coverage of the WNT4 gene. This advanced approach ensures detection of even rare genetic variants that might be missed by conventional testing methods.
Who Should Consider This Test
This genetic test is recommended for individuals presenting with the following clinical features:
- Ambiguous genitalia or disorders of sex development
- Renal abnormalities including kidney dysgenesis
- Adrenal gland dysfunction or insufficiency
- Lung development abnormalities
- Family history of similar developmental disorders
- Unexplained developmental delays with multi-organ involvement
Clinical Indications
Healthcare providers should consider ordering this test for pediatric patients with suspected genetic syndromes involving reproductive, renal, and adrenal systems. Early genetic diagnosis can significantly impact treatment planning and long-term management strategies.
Benefits of Taking the WNT4 Gene Test
- Accurate Diagnosis: Provides definitive genetic confirmation of SERKAL syndrome
- Personalized Treatment: Enables targeted medical management based on genetic findings
- Family Planning: Offers crucial information for genetic counseling and reproductive decisions
- Early Intervention: Facilitates timely medical interventions and monitoring
- Comprehensive Care: Supports multidisciplinary approach to complex medical needs
- Peace of Mind: Reduces diagnostic uncertainty for families and healthcare providers
Understanding Your Test Results
Our comprehensive genetic report provides detailed interpretation of your results with clinical context:
Positive Result
A positive result indicates the presence of a pathogenic mutation in the WNT4 gene consistent with SERKAL syndrome. This finding confirms the genetic basis of clinical symptoms and guides appropriate medical management.
Negative Result
A negative result suggests that no pathogenic variants were detected in the WNT4 gene. However, this does not completely rule out the possibility of SERKAL syndrome, as some genetic variants may not be detectable by current methods.
Variant of Uncertain Significance
Some results may identify genetic variants with unknown clinical significance. Our genetic counseling team provides guidance on interpretation and recommended follow-up testing.
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | WNT4 Gene SERKAL Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Specialty | Pediatrics |
| Department | Genetics |
| Method | NGS Technology |
| Disease Type | Dysmorphology |
Pre-Test Requirements
Before testing, we recommend:
- Complete clinical history of the patient
- Genetic counseling session to create a detailed family pedigree
- Discussion of potential implications and limitations of testing
- Informed consent process
Nationwide Testing Availability
We have convenient testing locations across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and healthcare professionals ensures accessible, high-quality genetic testing services nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let diagnostic uncertainty delay appropriate medical care. Our WNT4 Gene SERKAL Syndrome NGS Genetic DNA Test provides the genetic answers you need for informed medical decision-making. With our discounted price of $500 USD and comprehensive genetic analysis, you can move forward with confidence in your diagnosis and treatment plan.
Book Your Test Today
Ready to get started? Contact our genetic specialists to schedule your test and genetic counseling session. Call us at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process.
Take control of your genetic health today – accurate diagnosis leads to better outcomes.
