Vitamin D 1,25-Dihydroxy Test: Comprehensive Bone Health Assessment
Understanding the Vitamin D 1,25-Dihydroxy Test
The Vitamin D 1,25-Dihydroxy Test represents a sophisticated diagnostic tool that measures the biologically active form of vitamin D in your body. Unlike standard vitamin D tests that measure storage forms, this test specifically evaluates 1,25-dihydroxyvitamin D, the hormone that directly regulates calcium absorption and bone metabolism. This advanced assessment provides crucial insights into your body’s ability to convert vitamin D into its active form, making it essential for comprehensive bone health evaluation and metabolic assessment.
What Does This Test Measure?
This comprehensive assay measures both D2 and D3 components of 1,25-dihydroxyvitamin D, providing a complete picture of your vitamin D metabolism:
- Active Vitamin D Levels: Measures 1,25-dihydroxyvitamin D, the hormonally active form
- D2 Component Analysis: Evaluates vitamin D2 (ergocalciferol) from plant sources
- D3 Component Analysis: Assesses vitamin D3 (cholecalciferol) from animal sources and sunlight
- Metabolic Conversion Efficiency: Indicates how effectively your body converts vitamin D to its active form
Who Should Consider This Test?
This test is particularly valuable for individuals experiencing specific symptoms or with certain health conditions:
Symptoms Indicating Need for Testing
- Persistent bone pain or tenderness
- Muscle weakness and frequent cramping
- Unexplained fatigue and general malaise
- Bone fractures occurring with minimal trauma
- Dental problems and enamel defects
Medical Conditions Warranting Assessment
- Osteoporosis or osteomalacia diagnosis
- Chronic kidney disease affecting vitamin D metabolism
- Parathyroid disorders
- Malabsorption syndromes (Crohn’s disease, celiac disease)
- Liver conditions impacting vitamin D conversion
- Patients on long-term anticonvulsant therapy
Clinical Benefits of Vitamin D 1,25-Dihydroxy Testing
This advanced diagnostic assessment offers numerous clinical advantages:
- Accurate Bone Health Evaluation: Provides precise measurement of active vitamin D levels crucial for bone mineralization
- Metabolic Disorder Detection: Helps identify disorders affecting vitamin D activation
- Treatment Guidance: Informs appropriate vitamin D supplementation strategies
- Risk Assessment: Identifies individuals at risk for osteoporosis and fractures
- Monitoring Capability: Tracks treatment effectiveness for vitamin D-related conditions
Understanding Your Test Results
Interpreting your Vitamin D 1,25-Dihydroxy results requires professional medical guidance, but here’s a general overview:
Normal Range Interpretation
Normal levels typically range between 15-60 pg/mL, indicating adequate vitamin D activation and calcium regulation. Values within this range suggest proper metabolic conversion and sufficient active vitamin D for bone health maintenance.
Low Levels Significance
Levels below the normal range may indicate:
- Vitamin D deficiency despite adequate intake
- Impaired kidney function affecting activation
- Parathyroid hormone deficiencies
- Genetic disorders affecting vitamin D metabolism
Elevated Levels Implications
Higher than normal levels could suggest:
- Excessive vitamin D supplementation
- Hyperparathyroidism
- Sarcoidosis or other granulomatous diseases
- Certain lymphomas affecting vitamin D metabolism
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| Vitamin D 1,25-Dihydroxy Test – Discount Price | $112 |
| Vitamin D 1,25-Dihydroxy Test – Regular Price | $212 |
Convenient Testing Process
Our testing process is designed for maximum convenience and accuracy:
- Sample Collection: 3 mL (1.5 mL minimum) serum from 1 SST tube
- Preparation: No special preparation required – fast anytime
- Turnaround Time: Sample Monday through Saturday by 11 AM; Report Same Day
- Sample Handling: Ship refrigerated or frozen to maintain integrity
- Methodology: CLIA-certified testing ensuring highest accuracy standards
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible, reliable testing services wherever you are located.
Take Control of Your Bone Health Today
Don’t leave your bone health to chance. The Vitamin D 1,25-Dihydroxy Test provides essential insights into your metabolic health and bone integrity. With our special discounted price of $112 USD and same-day results, there’s never been a better time to assess your vitamin D status.
Ready to schedule your test? Contact us today:
Phone: +1(267) 388-9828
Booking: Available through our online portal or by phone
Our team of endocrine specialists and healthcare professionals is ready to assist you in understanding your results and developing an appropriate health management plan. Take the first step toward optimal bone health and metabolic wellness with GGC DNA’s comprehensive Vitamin D 1,25-Dihydroxy testing.

