TUBB2B Gene Polymicrogyria Asymmetric NGS Genetic DNA Test
Comprehensive Genetic Testing for Brain Development Disorders
The TUBB2B Gene Polymicrogyria Asymmetric NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for neurological conditions affecting brain development. This specialized test focuses on identifying mutations in the TUBB2B gene, which plays a critical role in neuronal migration and cortical development during fetal brain formation.
What is TUBB2B Gene Polymicrogyria?
Polymicrogyria is a complex brain malformation characterized by excessive folding of the brain’s surface and abnormal cortical layering. The asymmetric form specifically affects one hemisphere more than the other, leading to varied neurological manifestations. The TUBB2B gene encodes beta-tubulin, a fundamental protein essential for microtubule formation and proper neuronal migration during embryonic development.
What Does This Test Detect?
Our advanced NGS-based genetic test specifically identifies:
- Pathogenic variants in the TUBB2B gene associated with asymmetric polymicrogyria
- Missense mutations affecting tubulin protein function
- De novo and inherited genetic variations
- Specific nucleotide changes impacting brain development pathways
- Genetic markers for cortical malformation disorders
Who Should Consider This Test?
Clinical Indications and Symptoms
This genetic test is recommended for individuals presenting with:
- Developmental delays and intellectual disability
- Seizures or epilepsy of unknown origin
- Motor impairments and movement disorders
- Asymmetric brain findings on MRI scans
- Family history of brain malformations or neurological conditions
- Unexplained cerebral palsy-like symptoms
- Congenital neurological abnormalities
Key Benefits of Genetic Testing
Undergoing the TUBB2B gene test provides numerous advantages:
- Accurate Diagnosis: Confirms the genetic basis of neurological symptoms
- Treatment Guidance: Helps tailor appropriate therapeutic interventions
- Prognostic Information: Provides insight into disease progression and outcomes
- Family Planning: Enables informed reproductive decisions
- Early Intervention: Facilitates timely support and rehabilitation services
- Research Contribution: Advances understanding of rare neurological disorders
Understanding Your Test Results
Interpretation Guidelines
Our comprehensive genetic report includes:
- Positive Result: Indicates a pathogenic variant in the TUBB2B gene, confirming the genetic diagnosis of asymmetric polymicrogyria
- Negative Result: Suggests no detectable mutation in the TUBB2B gene, though other genetic causes should be considered
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Determines inheritance patterns for family members
All results are accompanied by detailed genetic counseling to ensure proper understanding and appropriate next steps.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | TUBB2B Gene Polymicrogyria Asymmetric NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of testing implications with healthcare provider
- Understanding of potential outcomes and their significance
Nationwide Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and healthcare professionals ensures accessible, high-quality care nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about neurological symptoms affect your quality of life. Our TUBB2B Gene Polymicrogyria Asymmetric NGS Genetic DNA Test provides the answers you need for informed medical decisions and comprehensive care planning.
Call us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our dedicated team is ready to guide you through every step of the testing process and help you understand your genetic health.
Early genetic diagnosis can make a significant difference in managing neurological conditions and improving long-term outcomes. Trust our expertise in pediatric genetics and dysmorphology to provide the comprehensive testing and support your family deserves.
