TGIF1 Gene Holoprosencephaly Type 4 NGS Genetic DNA Test
Comprehensive Genetic Testing for Brain Development Disorders
The TGIF1 Gene Holoprosencephaly Type 4 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for severe brain development disorders. This advanced genetic analysis utilizes cutting-edge Next Generation Sequencing technology to identify mutations in the TGIF1 gene, which plays a critical role in embryonic brain development and facial formation. Holoprosencephaly type 4 is a rare but serious condition where the brain fails to properly divide into two hemispheres during early fetal development.
What Does This Test Measure?
This comprehensive genetic test specifically targets and analyzes the TGIF1 (TGFB-Induced Factor Homeobox 1) gene using sophisticated NGS technology. The test detects:
- Point mutations and single nucleotide variants in the TGIF1 gene
- Small insertions and deletions affecting gene function
- Copy number variations that may impact gene expression
- Pathogenic variants associated with Holoprosencephaly type 4
- Inheritance patterns and carrier status information
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with:
- Newborns or children with craniofacial abnormalities including cleft lip/palate
- Individuals with midline facial defects such as single central incisor
- Patients with neurological symptoms including developmental delays
- Those with family history of Holoprosencephaly or related brain malformations
- Pregnant women with ultrasound findings suggesting fetal brain abnormalities
- Individuals with unexplained seizures or intellectual disability
- Couples with previous children affected by brain development disorders
Key Benefits of TGIF1 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out Holoprosencephaly type 4 with high precision
- Treatment Guidance: Helps healthcare providers develop targeted treatment plans
- Family Planning: Provides essential information for genetic counseling and reproductive decisions
- Early Intervention: Enables timely medical and therapeutic interventions
- Prognostic Information: Offers insights into potential disease progression and outcomes
- Research Contribution: Advances scientific understanding of rare genetic disorders
Understanding Your Test Results
Our comprehensive genetic counseling service helps you understand your results:
- Positive Result: Indicates the presence of a pathogenic TGIF1 mutation, confirming Holoprosencephaly type 4 diagnosis
- Negative Result: Suggests no detectable TGIF1 mutation, though other genetic causes may need investigation
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further study
- Carrier Status: Determines if you carry a single copy of the mutated gene without showing symptoms
All results are accompanied by detailed explanations and recommendations from our certified genetic counselors.
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | TGIF1 Gene Holoprosencephaly Type 4 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) Technology |
| Specialty | Pediatric Genetics |
Pre-Test Requirements
To ensure optimal testing accuracy, we require:
- Complete clinical history of the patient
- Genetic counseling session prior to testing
- Detailed pedigree chart of family members affected by similar conditions
- Informed consent for genetic testing
Nationwide Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and medical professionals ensures you receive the highest quality care regardless of your location.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about genetic conditions affect your family’s future. Our TGIF1 Gene Holoprosencephaly Type 4 NGS Genetic DNA Test provides the answers you need for informed medical decisions and peace of mind. With our discounted price of $500 USD and comprehensive genetic counseling included, you’re investing in your family’s health and future.
Ready to schedule your test? Contact us today:
Phone: +1(267) 388-9828
WhatsApp: +1(267) 388-9828
Our genetic specialists are available to answer your questions, discuss testing options, and help you schedule your appointment at a location convenient for you. Take control of your genetic health today with the most advanced TGIF1 testing available.
