TGFBR2 Gene Aortic Aneurysm Familial Thoracic Type 3 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Hereditary Aortic Conditions
The TGFBR2 Gene Aortic Aneurysm Familial Thoracic Type 3 NGS Genetic DNA Test represents a breakthrough in cardiovascular genetic diagnostics. This advanced test specifically targets mutations in the Transforming Growth Factor Beta Receptor 2 (TGFBR2) gene, which plays a critical role in maintaining the structural integrity of the aorta and other blood vessels. Familial thoracic aortic aneurysms type 3 is a serious inherited condition characterized by progressive weakening and dilation of the thoracic aorta, potentially leading to life-threatening complications such as aortic dissection or rupture if left undetected.
What This Test Measures and Detects
Our NGS-based genetic test provides comprehensive analysis of the TGFBR2 gene to identify pathogenic variants associated with familial thoracic aortic aneurysms type 3. The test specifically examines:
- Point mutations and small insertions/deletions in the TGFBR2 gene
- Genetic variants affecting TGF-β signaling pathway
- Mutations known to cause connective tissue abnormalities
- Inheritance patterns of aortic aneurysm predisposition
- Risk assessment for aortic dissection and related complications
Who Should Consider This Test
This genetic test is particularly recommended for individuals experiencing or concerned about:
- Family history of thoracic aortic aneurysms or dissections
- Unexplained chest pain or back pain
- Connective tissue disorder symptoms
- Marfan-like physical features without confirmed diagnosis
- Previous aortic surgery or intervention
- Relatives of individuals with confirmed TGFBR2 mutations
- Early-onset cardiovascular conditions
- Unexplained sudden cardiac death in family members
Clinical Benefits of Genetic Testing
Undergoing the TGFBR2 genetic test provides numerous clinical advantages:
- Early Detection: Identify genetic predisposition before symptoms develop
- Personalized Monitoring: Establish appropriate screening intervals based on genetic risk
- Family Planning: Make informed decisions about genetic inheritance
- Preventive Interventions: Implement lifestyle modifications and medical management
- Surgical Timing: Guide optimal timing for preventive aortic surgery
- Family Screening: Identify at-risk relatives who may benefit from testing
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic counselors and cardiovascular specialists. Possible outcomes include:
- Positive Result: A pathogenic mutation is identified, confirming increased risk for familial thoracic aortic aneurysms. This enables proactive medical management and regular monitoring.
- Negative Result: No known pathogenic mutations are detected, though continued clinical monitoring may still be recommended based on family history.
- Variant of Uncertain Significance: A genetic change is identified whose clinical significance is currently unknown. Additional family studies may be recommended.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessible genetic testing services for patients nationwide.
Take Control of Your Cardiovascular Health
Don’t wait for symptoms to develop. Early genetic testing for TGFBR2 mutations can provide life-saving information for you and your family. Our team of genetic counselors and cardiovascular specialists are available to discuss your results and develop a personalized management plan.
Book your TGFBR2 Gene Aortic Aneurysm Familial Thoracic Type 3 NGS Genetic DNA Test today by calling our dedicated genetic testing hotline at +1(267) 388-9828 or schedule your appointment online. Take the first step toward proactive cardiovascular health management and peace of mind for your family’s future.
