TCF12 Gene Craniosynostosis Type 3 NGS Genetic DNA Test
Comprehensive Genetic Testing for Craniosynostosis
The TCF12 Gene Craniosynostosis Type 3 NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for craniosynostosis disorders. This advanced test specifically targets mutations in the TCF12 gene, which plays a critical role in cranial suture development and maintenance. Craniosynostosis type 3, also known as Saethre-Chotzen syndrome, is a genetic condition characterized by the premature fusion of skull bones, leading to abnormal head shape and potential neurological complications.
What Does This Test Measure?
Our NGS-based genetic test comprehensively analyzes the TCF12 gene to identify pathogenic variants responsible for craniosynostosis type 3. The test detects:
- Point mutations in the TCF12 gene coding regions
- Small insertions and deletions affecting gene function
- Copy number variations impacting gene dosage
- Splice site mutations altering protein production
- Regulatory region variants affecting gene expression
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with:
- Abnormal skull shape or premature fontanelle closure in infants
- Family history of craniosynostosis or Saethre-Chotzen syndrome
- Facial asymmetry or dysmorphic facial features
- Ptosis (drooping eyelids) or other ocular abnormalities
- Syndactyly (fused fingers or toes)
- Developmental delays potentially linked to cranial abnormalities
- Planning for pregnancy with known family history
Clinical Benefits of Genetic Testing
Undergoing the TCF12 Gene Craniosynostosis Type 3 test provides numerous advantages:
- Accurate Diagnosis: Confirms genetic basis of craniosynostosis symptoms
- Family Planning: Enables informed reproductive decisions
- Early Intervention: Facilitates timely surgical and therapeutic management
- Genetic Counseling: Provides comprehensive risk assessment for family members
- Personalized Treatment: Guides appropriate medical and surgical approaches
- Peace of Mind: Reduces uncertainty about genetic inheritance patterns
Understanding Your Test Results
Our genetic counselors will help you interpret your results, which may include:
- Positive Result: Indicates presence of TCF12 gene mutation associated with craniosynostosis type 3
- Negative Result: Suggests no detectable mutation in the TCF12 gene
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Determines if you carry the mutation without showing symptoms
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Test Specifications
- Turnaround Time: 3 to 4 Weeks
- Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
- Methodology: Next-Generation Sequencing (NGS) Technology
- Specialty: Pediatrics and Genetics
- Department: Genetics
- Disease Type: Dysmorphology
Pre-Test Requirements
Before testing, we require:
- Complete clinical history of the patient
- Genetic counseling session to create family pedigree chart
- Documentation of affected family members with craniosynostosis symptoms
Nationwide Testing Availability
We have branches across all major cities in the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art genetic testing facilities ensure consistent, high-quality results nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about genetic conditions affect your family’s future. Our comprehensive TCF12 Gene Craniosynostosis Type 3 NGS Genetic DNA Test provides the answers you need for informed healthcare decisions. With our discounted price of $500 and expert genetic counseling support, you can gain valuable insights into your genetic health.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test appointment or to speak with our genetic counselors about your testing options.
Take control of your genetic health and ensure the best possible outcomes for you and your family. Book your test now and receive professional guidance every step of the way.
