TACR3 Gene Hypogonadotropic Hypogonadism Type 11 with or without Anosmia NGS Genetic DNA Test
Comprehensive Genetic Analysis for Reproductive Health
The TACR3 Gene Hypogonadotropic Hypogonadism Type 11 NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations associated with reproductive endocrine disorders. This specialized test utilizes Next-Generation Sequencing (NGS) technology to provide comprehensive analysis of the TACR3 gene, which plays a crucial role in the hypothalamic-pituitary-gonadal axis regulation.
What Does This Test Detect?
This advanced genetic test specifically targets mutations in the TACR3 gene, which encodes the neurokinin B receptor. When this gene contains pathogenic variants, it disrupts normal gonadotropin-releasing hormone (GnRH) secretion, leading to hypogonadotropic hypogonadism type 11. The test identifies:
- Point mutations in the TACR3 gene coding regions
- Insertions and deletions affecting gene function
- Pathogenic variants associated with Kallmann syndrome spectrum
- Genetic markers for anosmia (loss of smell) when present
Who Should Consider This Genetic Test?
Clinical Indications and Symptoms
This test is recommended for individuals presenting with:
- Delayed or absent puberty beyond age 14 in females and 15 in males
- Primary amenorrhea in females
- Infertility issues with unknown etiology
- Reduced or absent sense of smell (anosmia or hyposmia)
- Family history of hypogonadotropic hypogonadism
- Unexplained low levels of sex hormones (estrogen or testosterone)
- Delayed bone age and growth patterns
Benefits of TACR3 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms genetic basis for reproductive endocrine disorders
- Personalized Treatment: Enables targeted hormonal therapy approaches
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Early Intervention: Allows for timely management before complications develop
- Differential Diagnosis: Helps distinguish between various forms of hypogonadism
- Prognostic Information: Offers insights into long-term health management needs
Understanding Your Test Results
Interpretation Guidelines
Your genetic test results will fall into one of several categories:
- Positive Result: Identifies a pathogenic mutation in the TACR3 gene, confirming the genetic diagnosis of hypogonadotropic hypogonadism type 11
- Negative Result: No mutations detected in the TACR3 gene, suggesting other causes for symptoms
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: May identify individuals carrying one copy of a mutation without symptoms
All results should be interpreted in consultation with a qualified genetic counselor or endocrinology specialist who can provide personalized medical recommendations based on your specific genetic findings and clinical presentation.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | TACR3 Gene Hypogonadotropic Hypogonadism Type 11 with or without Anosmia NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Nationwide Testing Availability
We have diagnostic branches conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other cities. Our network ensures accessible genetic testing services regardless of your location.
Take Control of Your Reproductive Health
Don’t let unexplained reproductive symptoms or delayed development remain a mystery. Our TACR3 genetic test provides the clarity needed for proper diagnosis and treatment planning. With our discounted pricing at $500 USD and comprehensive genetic counseling support, you can make informed decisions about your health journey.
Ready to schedule your genetic test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to discuss your concerns, provide pre-test genetic counseling, and guide you through the testing process with compassion and expertise.
