STS Gene Ichthyosis X-Linked NGS Genetic DNA Test
Comprehensive Genetic Testing for Inherited Skin Disorders
The STS Gene Ichthyosis X-Linked NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for inherited dermatological conditions. This sophisticated test utilizes next-generation sequencing technology to analyze the STS (steroid sulfatase) gene, which plays a critical role in cholesterol sulfate metabolism and normal skin shedding processes. When mutations occur in this gene, they disrupt the natural exfoliation cycle of skin cells, leading to the characteristic symptoms of X-linked ichthyosis.
What Does This Test Measure and Detect?
This advanced genetic test specifically targets and sequences the entire STS gene to identify:
- Point mutations and single nucleotide variations
- Small insertions and deletions within the gene
- Complete or partial gene deletions
- Complex rearrangements affecting gene function
- Copy number variations impacting enzyme production
The test provides comprehensive coverage of all coding regions, splice sites, and regulatory elements of the STS gene, ensuring maximum detection sensitivity for clinically relevant variants associated with X-linked ichthyosis.
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals presenting with:
- Persistent generalized scaling and dryness of the skin
- Family history of X-linked ichthyosis or similar skin conditions
- Dark, polygonal scales primarily affecting the trunk and extremities
- Onset of symptoms shortly after birth or during early childhood
- Associated features such as corneal opacities or cryptorchidism
- Unexplained skin disorders that don’t respond to conventional treatments
Clinical Benefits of Genetic Testing
Undergoing the STS Gene Ichthyosis X-Linked NGS Genetic DNA Test offers numerous advantages:
- Accurate Diagnosis: Provides definitive confirmation of X-linked ichthyosis, eliminating diagnostic uncertainty
- Personalized Treatment: Enables development of targeted management strategies based on specific genetic findings
- Family Planning Guidance: Offers crucial information for genetic counseling and reproductive decision-making
- Early Intervention: Facilitates proactive management to minimize complications and improve quality of life
- Comprehensive Risk Assessment: Identifies carrier status in female relatives for informed family planning
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic specialists:
- Positive Result: Indicates the presence of a pathogenic mutation in the STS gene, confirming the diagnosis of X-linked ichthyosis
- Negative Result: Suggests no detectable mutations in the STS gene, though clinical correlation remains essential
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Carrier Status: For female relatives, determines whether they carry the mutation and risk passing it to offspring
All results include detailed interpretation and recommendations for clinical management, with genetic counseling available to help you understand the implications for your health and family.
Test Information and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | STS Gene Ichthyosis X-Linked NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
To ensure optimal testing outcomes, we recommend:
- Complete clinical history documentation of the patient
- Genetic counseling session to create a detailed family pedigree
- Discussion of testing implications with a qualified genetic counselor
- Informed consent process explaining benefits, limitations, and potential outcomes
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures easy access to this essential genetic testing service.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about your genetic health prevent you from getting the answers you need. Our team of genetic specialists and dermatologists are ready to help you understand your risk and develop an appropriate management plan.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or book your STS Gene Ichthyosis X-Linked NGS Genetic DNA Test online. Take control of your genetic health with comprehensive, accurate testing from America’s leading genetic diagnostics provider.
