SDHB Gene Paragangliomas Type 4 NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Paraganglioma Syndrome
The SDHB Gene Paragangliomas Type 4 NGS Genetic DNA Test represents a breakthrough in hereditary cancer risk assessment, specifically targeting mutations associated with paraganglioma-pheochromocytoma syndrome type 4. This sophisticated genetic analysis utilizes next-generation sequencing (NGS) technology to provide unparalleled accuracy in detecting SDHB gene mutations that predispose individuals to developing neuroendocrine tumors.
What This Advanced Genetic Test Measures
Our comprehensive NGS-based test specifically analyzes the SDHB (succinate dehydrogenase complex iron-sulfur subunit B) gene for pathogenic variants that cause hereditary paraganglioma-pheochromocytoma syndrome. The test detects:
- Point mutations and small insertions/deletions in the SDHB gene
- Copy number variations affecting SDHB gene function
- Novel genetic variants with potential clinical significance
- Inherited mutations that increase cancer susceptibility
Who Should Consider SDHB Genetic Testing
This test is particularly recommended for individuals experiencing:
- Personal history of paragangliomas or pheochromocytomas
- Family members diagnosed with SDHB-related cancers
- Unexplained hypertension or catecholamine excess symptoms
- Multiple neuroendocrine tumors at young age
- Metastatic paraganglioma without known primary tumor
- Family history of kidney cancer or gastrointestinal stromal tumors
Significant Benefits of Early Genetic Detection
Undergoing SDHB genetic testing provides numerous advantages:
- Proactive Cancer Prevention: Early identification enables targeted surveillance and preventive measures
- Personalized Treatment Planning: Results guide appropriate medical management strategies
- Family Risk Assessment: Identifies at-risk relatives who may benefit from testing
- Reduced Anxiety: Clear genetic information alleviates uncertainty about cancer risk
- Informed Reproductive Decisions: Supports family planning with genetic counseling
Understanding Your Test Results
Our comprehensive genetic report provides clear interpretation of your results:
- Positive Result: Indicates presence of SDHB mutation requiring enhanced surveillance and family testing
- Negative Result: No detected mutation, though continued monitoring may be recommended based on family history
- Variant of Uncertain Significance: Requires ongoing research and periodic re-evaluation
- Professional Genetic Counseling: Included with all results to ensure proper understanding and next steps
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your location.
Take Control of Your Genetic Health Today
Don’t wait to gain crucial insights into your hereditary cancer risk. Our SDHB Gene Paragangliomas Type 4 NGS Genetic DNA Test provides the advanced genetic information needed for informed healthcare decisions. Schedule your test today and take the first step toward proactive cancer prevention and personalized medical management.
Call or WhatsApp us now at +1(267) 388-9828 to book your comprehensive genetic assessment and receive professional genetic counseling.
