SCNN1G Gene Liddle Syndrome NGS Genetic DNA Test
Comprehensive Genetic Diagnosis for Inherited Hypertension
The SCNN1G Gene Liddle Syndrome NGS Genetic DNA Test represents a breakthrough in precision medicine for diagnosing rare inherited forms of hypertension. This advanced genetic screening utilizes cutting-edge Next Generation Sequencing technology to identify specific mutations in the SCNN1G gene that are responsible for Liddle syndrome, a serious autosomal dominant condition affecting kidney function and blood pressure regulation.
What Does This Test Measure?
This comprehensive genetic analysis specifically targets the SCNN1G gene, which encodes the gamma subunit of the epithelial sodium channel (ENaC). The test detects:
- Pathogenic variants and mutations in the SCNN1G gene
- Genetic alterations affecting sodium channel function
- Inherited patterns of Liddle syndrome transmission
- Specific nucleotide changes responsible for abnormal renal sodium reabsorption
Who Should Consider This Test?
This genetic test is particularly recommended for individuals presenting with:
- Early-onset hypertension before age 30
- Family history of hypertension across multiple generations
- Resistant hypertension unresponsive to conventional treatments
- Hypokalemia (low potassium levels) with hypertension
- Metabolic alkalosis associated with high blood pressure
- Suspected inherited renal tubular disorders
Clinical Benefits of Genetic Testing
Undergoing the SCNN1G Gene Liddle Syndrome test provides numerous advantages:
- Accurate diagnosis enabling targeted treatment with amiloride or triamterene
- Prevention of long-term complications including stroke and kidney damage
- Family planning guidance and genetic counseling opportunities
- Early intervention strategies for at-risk family members
- Personalized medication regimens avoiding ineffective treatments
- Comprehensive understanding of disease inheritance patterns
Understanding Your Test Results
Your genetic test report will provide detailed information about your SCNN1G gene status:
- Positive Result: Indicates presence of pathogenic mutation, confirming Liddle syndrome diagnosis and guiding specific treatment approaches
- Negative Result: Suggests absence of known SCNN1G mutations, though other genetic causes of hypertension may require investigation
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact, requiring ongoing monitoring and family studies
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Test Specifications
- Turnaround Time: 3 to 4 Weeks
- Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
- Methodology: Next Generation Sequencing (NGS) Technology
- Specialty: Genetics, Nephrology, Endocrinology
Pre-Test Requirements
Before scheduling your SCNN1G Gene Liddle Syndrome test, please ensure:
- Complete clinical history documentation
- Genetic counseling session to create family pedigree chart
- Discussion of potential implications with healthcare provider
- Understanding of insurance coverage and out-of-pocket costs
Nationwide Testing Availability
We proudly offer comprehensive genetic testing services across the United States with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your location.
Take Control of Your Genetic Health Today
Don’t let inherited hypertension conditions go undiagnosed. The SCNN1G Gene Liddle Syndrome NGS Genetic DNA Test provides the clarity needed for effective treatment planning and family health management. Our experienced genetic counselors and medical professionals are ready to guide you through the testing process and help interpret your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment and take the first step toward personalized hypertension management.
