SCN5A Gene Sick Sinus Syndrome Type 1 NGS Genetic DNA Test
Comprehensive Introduction to Cardiac Genetic Testing
The SCN5A Gene Sick Sinus Syndrome Type 1 NGS Genetic DNA Test represents a breakthrough in cardiovascular genetic diagnostics, offering precise identification of inherited heart rhythm disorders. This advanced genetic analysis focuses on the SCN5A gene, which encodes the alpha subunit of the cardiac sodium channel responsible for proper electrical conduction in the heart. When mutations occur in this critical gene, they can disrupt normal cardiac pacemaker function, leading to Sick Sinus Syndrome Type 1—a condition characterized by abnormal heart rhythms originating from the sinoatrial node.
This test is particularly important because early detection of SCN5A mutations can significantly impact treatment outcomes and prevent potentially life-threatening complications. By utilizing Next Generation Sequencing (NGS) technology, our laboratory provides comprehensive genetic analysis with exceptional accuracy and reliability, enabling healthcare providers to make informed decisions about patient care and management strategies.
What the Test Measures and Detects
The SCN5A Gene Sick Sinus Syndrome Type 1 NGS Genetic DNA Test specifically analyzes the entire coding region of the SCN5A gene to identify pathogenic variants associated with cardiac conduction abnormalities. Our advanced NGS methodology detects:
- Point mutations affecting sodium channel function
- Insertions and deletions disrupting gene structure
- Splice site mutations altering protein production
- Missense and nonsense mutations impacting channel physiology
- Complex genetic rearrangements affecting cardiac electrical activity
The test provides comprehensive coverage of all known pathogenic variants linked to Sick Sinus Syndrome Type 1, ensuring thorough assessment of genetic risk factors for cardiac rhythm disturbances.
Who Should Consider This Genetic Test
Clinical Indications and Symptoms
This genetic test is recommended for individuals presenting with symptoms suggestive of cardiac conduction abnormalities or those with family history of inherited heart conditions. Key candidates include:
- Patients experiencing unexplained syncope (fainting episodes)
- Individuals with documented bradycardia or tachycardia
- Those with family history of sudden cardiac death
- Patients requiring pacemaker implantation at young age
- Individuals with exercise intolerance and fatigue
- Those with documented sinus node dysfunction
- Family members of individuals with confirmed SCN5A mutations
Additional Risk Factors
Consider genetic testing if you have:
- Recurrent dizziness or lightheadedness
- Palpitations without clear cause
- Family history of inherited cardiac conditions
- Unexplained seizures or near-fainting episodes
- Abnormal ECG findings suggesting conduction disorders
Significant Benefits of Genetic Testing
Undergoing the SCN5A Gene Sick Sinus Syndrome Type 1 NGS Genetic DNA Test offers numerous advantages for comprehensive cardiac care:
- Accurate Diagnosis: Provides definitive genetic confirmation of Sick Sinus Syndrome Type 1
- Personalized Treatment: Enables tailored therapeutic approaches based on genetic findings
- Family Screening: Identifies at-risk relatives who may benefit from preventive measures
- Risk Stratification: Helps assess individual risk for cardiac complications
- Reproductive Planning: Assists in family planning decisions for inherited conditions
- Early Intervention: Facilitates timely management before serious complications develop
- Peace of Mind: Provides clarity and reduces uncertainty about cardiac symptoms
Understanding Your Genetic Test Results
Interpretation Guidelines
Our comprehensive genetic report provides detailed analysis of your SCN5A gene sequencing results with clear interpretation guidelines:
- Positive Result: Indicates presence of pathogenic mutation associated with Sick Sinus Syndrome Type 1, requiring cardiology consultation and specialized management
- Negative Result: Suggests absence of known pathogenic variants in SCN5A gene, though clinical evaluation remains important
- Variant of Uncertain Significance: Identifies genetic changes with unclear clinical impact, requiring ongoing monitoring and family studies
- Carrier Status: May identify individuals carrying mutations without current symptoms
Post-Test Recommendations
Following genetic testing, we recommend:
- Comprehensive genetic counseling session
- Cardiology evaluation and ongoing monitoring
- Family member testing when indicated
- Regular cardiac follow-up based on results
- Lifestyle modifications as recommended by healthcare provider
Test Information and Pricing
| Test Component | Details |
|---|---|
| Test Name | SCN5A Gene Sick Sinus Syndrome Type 1 NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next Generation Sequencing (NGS) Technology |
| Specialty | Cardiology and Genetics |
Pre-Test Requirements and Preparation
To ensure optimal testing outcomes, please prepare the following:
- Complete clinical history documentation
- Genetic counseling session prior to testing
- Family pedigree chart development
- Informed consent for genetic analysis
- Insurance pre-authorization if applicable
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take Control of Your Cardiac Health Today
Don’t let uncertainty about cardiac symptoms affect your quality of life. The SCN5A Gene Sick Sinus Syndrome Type 1 NGS Genetic DNA Test provides definitive answers and empowers you with knowledge about your genetic cardiac health. Our expert team of genetic counselors and cardiology specialists are ready to guide you through the testing process and help interpret your results.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Take the first step toward understanding your cardiac genetic profile and ensuring optimal heart health for years to come.
Our dedicated patient care coordinators are available to answer your questions, assist with insurance inquiries, and help you navigate the genetic testing process with confidence and ease.
