SCN1B Gene Familial Atrial Fibrillation Type 13 NGS Genetic DNA Test
Understanding SCN1B Gene Familial Atrial Fibrillation
The SCN1B Gene Familial Atrial Fibrillation Type 13 NGS Genetic DNA Test represents a breakthrough in cardiovascular genetic diagnostics. This specialized test focuses on identifying mutations in the SCN1B gene, which encodes the sodium channel beta-1 subunit protein crucial for proper cardiac electrical activity. When this gene malfunctions, it can lead to inherited forms of atrial fibrillation, a serious heart rhythm disorder affecting millions worldwide.
Atrial fibrillation is characterized by irregular and often rapid heart rate that can increase the risk of stroke, heart failure, and other heart-related complications. The familial type 13 variant specifically linked to SCN1B gene mutations follows an autosomal dominant inheritance pattern, meaning a single copy of the mutated gene from either parent can significantly increase the risk of developing this condition.
What This Test Detects and Measures
Our advanced NGS Genetic DNA Test specifically targets:
- Point mutations in the SCN1B gene coding regions
- Insertions and deletions affecting gene function
- Splice site variants that may alter protein production
- Pathogenic variants associated with familial atrial fibrillation type 13
- Genetic markers indicating increased susceptibility to cardiac arrhythmias
The test utilizes Next-Generation Sequencing technology, providing comprehensive analysis of the entire SCN1B gene with exceptional accuracy and sensitivity. This approach ensures detection of even rare genetic variants that might be missed by conventional testing methods.
Who Should Consider This Genetic Test?
Primary Candidates Include:
- Individuals with family history of atrial fibrillation, especially in multiple generations
- Patients experiencing unexplained heart palpitations or irregular heartbeat
- Those diagnosed with early-onset atrial fibrillation (before age 60)
- Family members of individuals with confirmed SCN1B gene mutations
- Patients with recurrent atrial fibrillation despite standard treatments
- Individuals planning pregnancy with family history of cardiac arrhythmias
Common Symptoms and Risk Factors:
- Heart palpitations or fluttering sensations
- Shortness of breath during normal activities
- Fatigue and reduced exercise tolerance
- Dizziness or lightheadedness
- Chest discomfort or pain
- Family history of sudden cardiac events
Significant Benefits of Genetic Testing
Undergoing the SCN1B Gene Familial Atrial Fibrillation Type 13 test provides numerous advantages:
Early Detection and Prevention
Identifying genetic predisposition allows for proactive monitoring and early intervention strategies. This can significantly reduce the risk of serious complications associated with untreated atrial fibrillation.
Personalized Treatment Planning
Genetic information enables cardiologists to develop targeted treatment approaches, including medication selection, lifestyle modifications, and monitoring frequency tailored to your specific genetic profile.
Family Risk Assessment
Test results provide valuable information for family members, helping them understand their own genetic risk and take appropriate preventive measures.
Reproductive Planning
For individuals considering starting a family, genetic testing provides crucial information about the risk of passing the condition to future generations.
Understanding Your Test Results
Our comprehensive genetic counseling services ensure you fully understand your test results and their implications:
Positive Result Interpretation
A positive result indicates the presence of a pathogenic SCN1B gene mutation associated with familial atrial fibrillation type 13. This doesn’t guarantee you will develop the condition, but significantly increases your risk. Our genetic counselors will discuss:
- Specific mutation characteristics and associated risks
- Recommended monitoring and screening protocols
- Lifestyle modifications to reduce risk factors
- Treatment options if symptoms develop
- Family testing recommendations
Negative Result Interpretation
A negative result means no known pathogenic SCN1B mutations were detected. However, this doesn’t completely eliminate the risk of developing atrial fibrillation through other genetic or environmental factors. Our team will discuss:
- Continued cardiac health monitoring recommendations
- Other potential genetic factors not covered by this specific test
- General cardiovascular health maintenance strategies
Variant of Uncertain Significance (VUS)
Sometimes, genetic changes are identified whose clinical significance is currently unknown. In such cases, we provide:
- Detailed explanation of the uncertainty
- Recommendations for additional family member testing
- Plans for periodic re-evaluation as research advances
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | SCN1B Gene Familial Atrial Fibrillation Type 13 NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
| Specialty | Cardiology & Genetics |
Pre-Test Requirements and Preparation
To ensure accurate results and comprehensive care, we require:
- Complete clinical history of the patient
- Genetic counseling session to create detailed family pedigree chart
- Documentation of family members affected by cardiac conditions
- Review of current medications and medical conditions
Nationwide Accessibility
We have conveniently located branches across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network ensures you receive the same high-quality genetic testing and counseling services regardless of your location.
Take Control of Your Cardiac Health Today
Don’t let uncertainty about your genetic risk for atrial fibrillation compromise your health and peace of mind. Our SCN1B Gene Familial Atrial Fibrillation Type 13 NGS Genetic DNA Test provides the clarity you need to make informed decisions about your cardiac health.
Call us now at +1(267) 388-9828 to schedule your genetic counseling session and test appointment. Our experienced genetic counselors and cardiology specialists are ready to guide you through the testing process and help you understand your results in the context of your overall health.
Early detection through genetic testing can be life-saving. Take the first step toward personalized cardiac care and family health planning by booking your test today. Our team is committed to providing compassionate, comprehensive care throughout your genetic testing journey.
