SCA8 Spinocerebellar Ataxia ATXN8OS ATXN8 Gene Mutation Test
Comprehensive Genetic Testing for Spinocerebellar Ataxia Type 8
The SCA8 Spinocerebellar Ataxia ATXN8OS ATXN8 Gene Mutation Test represents a cutting-edge diagnostic solution for individuals concerned about inherited neurological conditions. Spinocerebellar Ataxia Type 8 is an autosomal dominant neurodegenerative disorder characterized by progressive impairment of coordination, balance, and motor function. This specialized genetic test provides definitive answers for patients experiencing unexplained neurological symptoms or those with family histories of ataxia disorders.
What This Test Measures and Detects
Our advanced molecular diagnostic test specifically targets two critical genetic components:
- ATXN8OS CTG Repeat Analysis: Detects abnormal expansions in the CTG trinucleotide repeat sequence within the ATXN8OS gene
- ATXN8 CAG Repeat Analysis: Identifies mutations in the CAG repeat region of the ATXN8 gene
Using sophisticated PCR and fragment analysis technology, our laboratory precisely measures the number of repeat sequences in both genes. Normal individuals typically have fewer than 80 CTG repeats in ATXN8OS and normal CAG repeats in ATXN8, while affected individuals demonstrate significant expansions beyond these thresholds.
Who Should Consider SCA8 Genetic Testing
This test is particularly recommended for individuals experiencing:
- Unexplained coordination difficulties and balance problems
- Progressive speech impairment or slurred speech
- Family history of spinocerebellar ataxia or similar neurological disorders
- Involuntary eye movements (nystagmus)
- Difficulty with fine motor tasks and handwriting changes
- Planning future family decisions with known ataxia risk factors
- Unexplained gait abnormalities developing in adulthood
Significant Benefits of SCA8 Testing
Undergoing SCA8 genetic testing provides numerous advantages for patients and healthcare providers:
- Definitive Diagnosis: Eliminates uncertainty and provides clear genetic confirmation
- Early Intervention: Enables proactive management and treatment planning
- Family Planning Guidance: Informs reproductive decisions and genetic counseling
- Symptom Management: Facilitates targeted therapies and rehabilitation strategies
- Research Contribution: Advances scientific understanding of neurodegenerative disorders
- Peace of Mind: Provides clarity for symptomatic individuals and at-risk family members
Understanding Your Test Results
Our comprehensive reporting provides clear interpretation of your genetic findings:
- Normal Result: No abnormal expansions detected in ATXN8OS or ATXN8 genes
- Abnormal Result: Significant CTG or CAG repeat expansions consistent with SCA8 diagnosis
- Intermediate Range: Repeat numbers that may require clinical correlation
- Genetic Counseling: All positive results include recommendations for specialized genetic counseling
Our neurologists and genetic specialists provide detailed explanations of your results and their clinical implications, ensuring you fully understand the findings and next steps.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $188 |
| Regular Price | $376 |
Convenient Nationwide Access
We have diagnostic centers conveniently located throughout the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our state-of-the-art facilities ensure consistent, high-quality testing standards across all locations.
Take Control of Your Neurological Health Today
Don’t let uncertainty about neurological symptoms affect your quality of life. Our SCA8 Spinocerebellar Ataxia genetic test provides the answers you need for informed healthcare decisions. With rapid turnaround times (sample by Tuesday 11 AM, report by Saturday) and expert genetic counseling support, we make advanced neurological diagnostics accessible and understandable.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward clarity and proactive neurological health management.
Note: This test requires 4 mL (2 mL minimum) whole blood in 1 Lavender top (EDTA) tube shipped refrigerated. DO NOT FREEZE samples. A duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory for all testing.
