RPL21 Gene Hypotrichosis Type 12 NGS Genetic DNA Test
Comprehensive Genetic Analysis for Hereditary Hair Loss Conditions
The RPL21 Gene Hypotrichosis Type 12 NGS Genetic DNA Test represents a significant advancement in the diagnosis and understanding of hereditary hair loss disorders. This specialized genetic test focuses on identifying mutations in the RPL21 gene, which plays a crucial role in ribosomal protein synthesis and has been directly linked to hypotrichosis type 12 – a rare autosomal recessive condition characterized by sparse scalp hair and abnormal hair shaft development.
What Does This Test Measure?
This comprehensive genetic analysis utilizes Next-Generation Sequencing (NGS) technology to examine the complete coding region of the RPL21 gene for pathogenic variants. The test specifically detects:
- Point mutations and small insertions/deletions in the RPL21 gene
- Pathogenic variants associated with hypotrichosis type 12
- Genetic markers for autosomal recessive inheritance patterns
- Specific nucleotide changes affecting ribosomal protein function
Who Should Consider This Test?
This genetic test is recommended for individuals presenting with:
- Congenital or early-onset sparse scalp hair
- Family history of hereditary hair loss conditions
- Abnormal hair shaft morphology and texture
- Progressive hair thinning beginning in childhood
- Consanguineous parentage with hair disorder history
- Unexplained hair loss patterns not responsive to conventional treatments
Clinical Benefits and Applications
Undergoing the RPL21 Gene Hypotrichosis Type 12 test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out genetic causes of hair loss
- Genetic Counseling: Enables informed family planning decisions
- Personalized Management: Guides appropriate treatment strategies
- Prognostic Information: Helps predict disease progression
- Research Contribution: Advances understanding of rare genetic disorders
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our team of certified genetic counselors and dermatology specialists:
- Positive Result: Indicates the presence of pathogenic RPL21 gene mutations, confirming hypotrichosis type 12 diagnosis
- Negative Result: Suggests absence of tested mutations, though other genetic or environmental factors may contribute to hair loss
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Determines if you carry one copy of a mutated gene without showing symptoms
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Pre-Test Requirements
Before undergoing testing, patients should provide:
- Complete clinical history related to hair loss symptoms
- Participation in genetic counseling session
- Detailed family pedigree chart documenting affected relatives
- Informed consent for genetic testing
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified collection centers ensures accessible genetic testing services nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about hereditary hair loss conditions affect your quality of life. Our specialized genetic testing provides the answers you need for proper diagnosis and management. Contact our genetic counseling team today to schedule your RPL21 Gene Hypotrichosis Type 12 NGS Genetic DNA Test.
Call or WhatsApp: +1(267) 388-9828
Book Your Test Today for Comprehensive Genetic Insight
Our team of board-certified genetic counselors and dermatology specialists are ready to guide you through the testing process and help interpret your results for optimal clinical management of hereditary hair disorders.
