REN Gene Renal Tubular Dysgenesis NGS Genetic DNA Test
Comprehensive Genetic Testing for Kidney Development Disorders
The REN Gene Renal Tubular Dysgenesis NGS Genetic DNA Test represents a breakthrough in molecular diagnostics for rare kidney disorders. This sophisticated genetic analysis utilizes next-generation sequencing technology to detect mutations in the REN gene, which plays a critical role in kidney development and function. Renal tubular dysgenesis is a severe autosomal recessive disorder characterized by abnormal development of renal tubules, leading to profound renal insufficiency and often fatal outcomes in the perinatal period.
What This Advanced Genetic Test Measures
Our comprehensive NGS genetic test specifically targets the REN gene, which encodes renin—a key enzyme in the renin-angiotensin-aldosterone system (RAAS). This system regulates blood pressure, electrolyte balance, and renal blood flow. The test detects:
- Point mutations, insertions, and deletions in the REN gene
- Autosomal recessive inheritance patterns
- Pathogenic variants affecting renin production and function
- Genetic markers associated with renal tubular development abnormalities
Who Should Consider This Genetic Test
This specialized genetic testing is recommended for individuals presenting with:
- Unexplained perinatal renal failure or oliguria
- Family history of renal tubular dysgenesis or similar kidney disorders
- Prenatal ultrasound findings of oligohydramnios or Potter sequence
- Persistent hypotension unresponsive to conventional treatments
- Consanguineous parents with suspected autosomal recessive disorders
- Previous siblings with unexplained neonatal death due to renal failure
Significant Benefits of Genetic Testing
Undergoing the REN Gene Renal Tubular Dysgenesis NGS Genetic DNA Test provides numerous advantages:
- Accurate Diagnosis: Provides definitive molecular confirmation of renal tubular dysgenesis
- Family Planning Guidance: Enables informed reproductive decisions for at-risk families
- Early Intervention: Facilitates prompt medical management and specialized care
- Genetic Counseling: Offers comprehensive risk assessment and inheritance pattern explanation
- Research Contribution: Advances understanding of rare kidney development disorders
Understanding Your Genetic Test Results
Our expert genetic counselors provide detailed interpretation of your results:
- Positive Result: Indicates pathogenic mutations in the REN gene, confirming renal tubular dysgenesis diagnosis
- Negative Result: Suggests absence of detectable REN gene mutations, though other genetic causes may be considered
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Identifies individuals with single mutation copies who may pass the condition to offspring
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Turnaround Time: 3 to 4 Weeks
Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
Nationwide Testing Accessibility
We have branches across the United States, making advanced genetic testing accessible in major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic counselors and specialized laboratories ensures consistent, high-quality testing services nationwide.
Take Action for Your Genetic Health
Don’t wait to get the answers you need for proper diagnosis and treatment planning. Our comprehensive genetic testing services include pre-test genetic counseling to create detailed family pedigree charts and explain the implications of testing. Contact us today to schedule your appointment and take the first step toward understanding your genetic health.
Call or WhatsApp: +1(267) 388-9828
Book your REN Gene Renal Tubular Dysgenesis NGS Genetic DNA Test today and receive expert genetic counseling alongside precise molecular diagnostics.
