RAG1 Gene Severe Combined Immunodeficiency B Cell-Negative NGS Genetic DNA Test
Comprehensive Introduction to RAG1 Gene Testing
The RAG1 Gene Severe Combined Immunodeficiency B Cell-Negative NGS Genetic DNA Test represents a breakthrough in immunological diagnostics, offering precise detection of genetic mutations that cause severe immune system deficiencies. This advanced testing methodology provides critical insights for patients and healthcare providers dealing with complex immune disorders.
What Does This Test Measure?
This sophisticated genetic analysis specifically targets mutations in the RAG1 (Recombination Activating Gene 1) gene, which plays a fundamental role in the development and function of the immune system. The test utilizes Next-Generation Sequencing (NGS) technology to identify:
- Point mutations in the RAG1 gene coding regions
- Deletions and insertions affecting gene function
- Genetic variations impacting V(D)J recombination processes
- Mutations leading to B-cell deficiency and T-cell abnormalities
Who Should Consider This Test?
This specialized genetic test is recommended for individuals presenting with specific clinical indications:
- Infants and children with recurrent, severe infections
- Patients with failure to thrive and developmental delays
- Individuals with family history of immune deficiency disorders
- Patients with unexplained autoimmune manifestations
- Those with abnormal lymphocyte counts or function
- Individuals with suspected primary immunodeficiency diseases
Clinical Symptoms Indicating Testing Need
Common symptoms that warrant consideration of RAG1 gene testing include:
- Persistent respiratory infections requiring hospitalization
- Chronic diarrhea and gastrointestinal complications
- Severe skin rashes and dermatological manifestations
- Recurrent fungal or viral infections
- Poor response to standard antibiotic treatments
- Growth retardation and developmental concerns
Significant Benefits of RAG1 Gene Testing
Undergoing this comprehensive genetic analysis provides multiple advantages:
- Early Diagnosis: Enables prompt identification of immune deficiencies before severe complications develop
- Personalized Treatment: Guides targeted therapeutic interventions and management strategies
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Prognostic Value: Helps predict disease progression and potential outcomes
- Preventive Care: Facilitates implementation of preventive measures against infections
- Treatment Monitoring: Assists in evaluating response to immunomodulatory therapies
Understanding Your Test Results
Our comprehensive reporting system provides clear interpretation of your genetic findings:
- Positive Result: Indicates presence of pathogenic RAG1 gene mutations requiring specialized immunological care
- Negative Result: Suggests absence of detectable RAG1 mutations, though other immune disorders may need evaluation
- Variant of Uncertain Significance: Identifies genetic changes requiring further clinical correlation
- Carrier Status: Determines if individuals carry mutations without showing symptoms
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| RAG1 Gene Severe Combined Immunodeficiency B Cell-Negative NGS Genetic DNA Test – Discount Price | $500 |
| RAG1 Gene Severe Combined Immunodeficiency B Cell-Negative NGS Genetic DNA Test – Regular Price | $700 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network of certified collection centers ensures accessibility for patients nationwide.
Take Action for Your Immune Health
Don’t wait to address potential immune system concerns. Early detection through RAG1 gene testing can significantly impact treatment outcomes and quality of life. Our experienced genetic counselors and immunology specialists are ready to guide you through the testing process and help interpret your results.
Call us today at +1(267) 388-9828 to schedule your RAG1 Gene Severe Combined Immunodeficiency B Cell-Negative NGS Genetic DNA Test or book your appointment online. Take the first step toward comprehensive immune health assessment and personalized care.
