Protein C Antigen Test: Comprehensive Coagulation Disorder Screening
Understanding Protein C Antigen Testing
The Protein C Antigen Test is a sophisticated diagnostic examination that plays a critical role in evaluating your body’s natural anticoagulation system. Protein C is an essential vitamin K-dependent plasma protein synthesized in the liver that functions as a key regulator in the coagulation cascade. This vital protein works in conjunction with Protein S to inactivate clotting factors Va and VIIIa, thereby preventing excessive blood clot formation and maintaining proper hemostatic balance.
What Does the Protein C Antigen Test Measure?
This specialized laboratory test precisely quantifies the concentration of Protein C antigen in your blood plasma. Unlike functional Protein C tests that assess enzymatic activity, the antigen test specifically measures the actual protein quantity present in your bloodstream. The test detects:
- Total Protein C antigen levels in plasma
- Quantitative measurement of Protein C concentration
- Presence of Type I deficiencies (reduced antigen and activity)
- Baseline Protein C levels for treatment monitoring
Who Should Consider Protein C Antigen Testing?
Several clinical scenarios warrant Protein C Antigen testing to ensure comprehensive coagulation assessment:
Clinical Indications and Symptoms
- Patients with unexplained venous thromboembolism (VTE)
- Individuals experiencing recurrent deep vein thrombosis (DVT)
- Those with pulmonary embolism without clear risk factors
- Patients with family history of thrombophilia or clotting disorders
- Individuals with warfarin-induced skin necrosis
- Neonates and infants with purpura fulminans
- Patients planning major surgical procedures with thrombotic risk
- Women with recurrent pregnancy complications or miscarriages
Benefits of Protein C Antigen Testing
Undergoing Protein C Antigen testing provides numerous clinical advantages for comprehensive healthcare management:
Diagnostic and Therapeutic Benefits
- Early Detection: Identifies Protein C deficiencies before thrombotic events occur
- Personalized Treatment: Guides appropriate anticoagulation therapy selection
- Risk Assessment: Evaluates thrombotic risk for surgical planning
- Family Screening: Helps identify hereditary coagulation disorders in relatives
- Treatment Monitoring: Tracks Protein C levels during anticoagulant therapy
- Preventive Care: Enables proactive management to prevent life-threatening clots
Understanding Your Test Results
Proper interpretation of Protein C Antigen test results requires professional medical expertise, but general guidance includes:
Result Interpretation Guidelines
- Normal Range: Typically 70-130% of normal plasma concentration indicates adequate Protein C levels
- Mild Deficiency: 50-70% may suggest heterozygous deficiency or acquired conditions
- Moderate Deficiency: 30-50% often indicates significant Protein C deficiency
- Severe Deficiency: Below 30% suggests homozygous deficiency or severe acquired deficiency
- Elevated Levels: May occur in certain inflammatory conditions or as acute phase reactants
Always consult with your hematologist or healthcare provider for comprehensive result interpretation and personalized treatment recommendations based on your complete clinical picture.
Test Pricing and Availability
| Test Description | Regular Price | Discount Price |
|---|---|---|
| Protein C Antigen Test | $626 USD | $450 USD |
Nationwide Testing Availability
GGC DNA provides comprehensive Protein C Antigen testing services across the United States. We have conveniently located branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other cities. Our state-of-the-art laboratories ensure accurate and reliable results with rapid turnaround times.
Sample Collection and Processing
For optimal test accuracy, proper sample collection and handling are essential:
Sample Requirements
- Sample Type: 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube
- Processing: Mix thoroughly by inversion immediately after collection
- Transport: Deliver to laboratory within 4 hours of collection
- Alternative Processing: If immediate transport isn’t possible, prepare platelet-poor plasma (PPP) within 1 hour
- Storage: Freeze immediately and ship frozen – DO NOT THAW
Required Documentation
Complete Coagulation Requisition Form (Form 15) AND Test Send Out Consent Form (Form 35) are mandatory for processing. Our trained phlebotomists ensure proper sample collection following strict quality control protocols.
Take Control of Your Coagulation Health Today
Don’t leave your coagulation health to chance. The Protein C Antigen Test provides crucial insights into your body’s natural anticoagulation system, helping prevent serious thrombotic complications. Our experienced hematology specialists and advanced immunoassay technology ensure the highest level of diagnostic accuracy.
Ready to schedule your Protein C Antigen Test? Contact our dedicated healthcare team today to book your appointment or discuss your testing needs. Call or WhatsApp us at +1(267) 388-9828 for immediate assistance and personalized consultation.
Early detection through comprehensive Protein C Antigen testing can make a significant difference in managing your coagulation health and preventing potentially life-threatening thrombotic events. Trust GGC DNA for accurate, reliable, and timely coagulation disorder diagnostics.
