Prenatal Diagnostic Screening by Karyotyping and FISH for Chromosomes 13, 18, 21, X and Y
Comprehensive Prenatal Chromosomal Analysis
Prenatal Diagnostic Screening by Karyotyping and FISH represents the gold standard in chromosomal analysis during pregnancy. This sophisticated diagnostic approach combines two powerful genetic testing methodologies to provide comprehensive insights into fetal chromosomal health. By examining chromosomes 13, 18, 21, X, and Y, this test offers crucial information about potential genetic abnormalities that could impact fetal development and pregnancy outcomes.
What This Advanced Screening Measures
Our prenatal diagnostic screening utilizes cutting-edge genetic technologies to detect chromosomal abnormalities with exceptional accuracy:
- Karyotyping Analysis: Provides a complete chromosomal picture by examining the number, size, and structure of all 46 chromosomes
- FISH Technology: Fluorescence In Situ Hybridization offers rapid detection of specific chromosomal abnormalities in chromosomes 13, 18, 21, X, and Y
- Numerical Abnormalities: Detects extra or missing chromosomes (aneuploidies) that cause conditions like Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), and Patau syndrome (trisomy 13)
- Sex Chromosome Analysis: Identifies abnormalities in X and Y chromosomes that can affect sexual development and overall health
Who Should Consider This Prenatal Screening?
This comprehensive chromosomal analysis is particularly recommended for:
- Women with abnormal first or second trimester screening results
- Advanced maternal age (35 years or older)
- Previous pregnancy with chromosomal abnormalities
- Family history of genetic disorders
- Abnormal ultrasound findings suggesting chromosomal issues
- Parents with balanced chromosomal rearrangements
- Couples with recurrent pregnancy loss
Clinical Indications and Risk Factors
Several factors may indicate the need for this advanced prenatal screening:
- Increased nuchal translucency on ultrasound
- Structural abnormalities detected during fetal ultrasound
- Abnormal maternal serum screening results
- Parental anxiety about genetic conditions
- Exposure to potential teratogens during pregnancy
Significant Benefits of Prenatal Chromosomal Screening
Choosing this comprehensive diagnostic approach offers numerous advantages for expectant parents:
- Early Detection: Identifies chromosomal abnormalities early in pregnancy, allowing for informed decision-making
- Comprehensive Analysis: Combines two complementary technologies for maximum detection accuracy
- Rapid Preliminary Results: FISH provides quick initial findings within 2-3 days for critical chromosomes
- Complete Chromosomal Picture: Karyotyping delivers detailed analysis of all chromosomal structures
- Peace of Mind: Provides reassurance about fetal chromosomal health
- Preparation Opportunity: Allows families to prepare for potential special needs
- Informed Medical Management: Enables appropriate pregnancy and delivery planning
Understanding Your Test Results
Interpreting your prenatal screening results requires professional medical guidance:
- Normal Results: Indicate typical chromosomal patterns with no detected abnormalities in the tested chromosomes
- Abnormal Findings: May reveal numerical or structural chromosomal abnormalities requiring further evaluation
- Genetic Counseling: All abnormal results include comprehensive genetic counseling sessions
- Follow-up Testing: Additional testing may be recommended based on initial findings
- Clinical Correlation: Results are interpreted in context with ultrasound findings and clinical presentation
Test Pricing and Procedure Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $338 |
| Regular Price | $450 |
Test Specifications
- Turnaround Time: 15-20 days for complete analysis
- Sample Type: Amniotic fluid or Chorionic tissue samples
- Test Components: 2 sterile tubes (15 ml each) / Sterile tissue culture container with normal saline or culture media
- Methodology: Cell culture combined with FISH technology
- Specialty: Prenatal Genetics under Gynecologist supervision
Nationwide Accessibility and Booking
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality results regardless of your location.
Pre-Test Requirements
This prenatal diagnostic screening requires a physician’s prescription, except for surgical cases, pregnancy-related testing, or individuals planning international travel. Our genetic counselors are available to discuss testing indications and answer any questions you may have about the procedure.
Take the Next Step in Prenatal Care
Ensure comprehensive chromosomal assessment for your pregnancy with our advanced Karyotyping and FISH screening. Our experienced genetic specialists and state-of-the-art technology provide the accurate information you need for informed pregnancy management.
Schedule your prenatal diagnostic screening today by calling our genetic counseling team at +1(267) 388-9828 or booking your appointment online. Take advantage of our special pricing at only $338 USD and gain peace of mind about your baby’s chromosomal health.
