PIIINP Procollagen Type III Amino Terminal Propeptide Test
Understanding the PIIINP Test
The PIIINP Procollagen Type III Amino Terminal Propeptide Test represents a cutting-edge diagnostic approach for evaluating fibrotic processes and connective tissue disorders. This specialized blood test measures the levels of procollagen type III amino-terminal propeptide (PIIINP), a crucial biomarker that provides direct insight into collagen synthesis and tissue remodeling activities throughout the body.
Collagen type III is a fundamental structural protein found in various tissues, particularly in the skin, blood vessels, and internal organs. When tissue damage or inflammation occurs, the body initiates repair processes that involve increased collagen production. PIIINP is cleaved from the newly formed procollagen type III molecules and released into the bloodstream, making it an excellent indicator of active fibrogenesis and tissue remodeling.
What the PIIINP Test Measures
This advanced diagnostic test specifically detects and quantifies:
- PIIINP levels in serum, reflecting active collagen type III synthesis
- Fibrotic activity in liver tissue and other organs
- Connective tissue remodeling processes
- Disease progression in various fibrotic conditions
- Treatment response in patients undergoing antifibrotic therapy
Who Should Consider This Test
Clinical Indications and Symptoms
The PIIINP test is particularly valuable for individuals experiencing:
- Unexplained liver enzyme abnormalities or suspected liver fibrosis
- Progressive skin thickening or tightening (scleroderma symptoms)
- Chronic inflammatory conditions affecting connective tissues
- Monitoring of established fibrotic diseases
- Assessment of treatment effectiveness for fibrotic disorders
- Evaluation of disease activity in systemic sclerosis patients
Specialty Referrals
This test is commonly ordered by:
- Dermatologists evaluating skin fibrosis and connective tissue diseases
- Gastroenterologists monitoring liver fibrosis progression
- Rheumatologists managing systemic autoimmune conditions
- Hepatologists assessing chronic liver disease severity
Benefits of Taking the PIIINP Test
Choosing the PIIINP Procollagen Type III Amino Terminal Propeptide Test offers numerous advantages:
- Early Detection: Identifies fibrotic processes before advanced tissue damage occurs
- Disease Monitoring: Tracks disease progression and treatment response over time
- Non-Invasive Assessment: Provides valuable information without requiring invasive biopsies
- Personalized Treatment: Helps guide targeted therapeutic interventions
- Prognostic Value: Offers insights into disease course and potential outcomes
- Comprehensive Evaluation: Complements other diagnostic markers for complete assessment
Understanding Your Test Results
Interpreting PIIINP Levels
Your PIIINP test results will provide valuable information about collagen synthesis activity:
- Normal Range: Indicates typical collagen turnover without significant fibrotic activity
- Elevated Levels: Suggests increased collagen synthesis, potentially indicating active fibrosis or tissue remodeling
- Significantly Elevated: May indicate progressive fibrotic disease requiring immediate attention
- Trend Analysis: Serial measurements help monitor disease activity and treatment response
Clinical Correlation
It’s essential to interpret PIIINP results in the context of:
- Clinical symptoms and physical examination findings
- Other laboratory markers and imaging studies
- Patient’s overall health status and medical history
- Concurrent medications and treatments
Test Pricing and Details
| Test Name | Discount Price | Regular Price |
|---|---|---|
| PIIINP Procollagen Type III Amino Terminal Propeptide Test | $138 USD | $212 USD |
Test Specifications
- Turnaround Time: Sample submission Monday/Thursday by 4 PM; Report available next day
- Sample Type: 3 mL (1.5 mL minimum) serum from 1 SST tube
- Shipping Requirements: Ship refrigerated or frozen
- Pre-test Instructions: Overnight fasting is preferred
- Testing Method: CLIA-certified laboratory
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas. Our network includes specialized collection centers in:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and the Midwest region
- Houston, Dallas, and Texas locations
- Miami, Orlando, and Florida centers
- Phoenix, Las Vegas, and Southwest facilities
- Seattle, Portland, and Pacific Northwest sites
Take Control of Your Health Today
The PIIINP Procollagen Type III Amino Terminal Propeptide Test provides crucial insights into your connective tissue health and fibrotic processes. With our discounted price of only $138 USD and comprehensive nationwide coverage, accessing this advanced diagnostic testing has never been more convenient.
Ready to schedule your test? Contact our dedicated healthcare team today to book your appointment or discuss your testing needs. Call or WhatsApp us at +1(267) 388-9828 to speak with a specialist who can answer your questions and help you take the next step toward better health management.
Don’t wait to get the answers you need about your connective tissue health. Early detection and monitoring of fibrotic conditions can significantly impact treatment outcomes and quality of life. Trust our experienced team and state-of-the-art CLIA-certified laboratory to provide accurate, reliable results you can depend on.

