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PCSK1 Gene Obesity with Impaired Prohormone Processing NGS Genetic DNA Test

Original price was: $700.Current price is: $500.

-29%

The PCSK1 Gene Obesity with Impaired Prohormone Processing NGS Genetic DNA Test is a cutting-edge diagnostic tool that identifies mutations in the PCSK1 gene responsible for severe early-onset obesity. This comprehensive genetic analysis uses Next-Generation Sequencing (NGS) technology to detect abnormalities in prohormone convertase 1/3 enzyme function, which plays a critical role in appetite regulation and metabolic processes. Individuals with unexplained severe obesity, particularly those with childhood onset and family history, benefit from this test by gaining insights into their genetic predisposition. The test provides valuable information for personalized treatment approaches and helps identify underlying genetic causes of obesity that may not respond to conventional weight management strategies. At $500 USD, this advanced genetic testing offers affordable access to specialized obesity diagnostics across our nationwide network of testing centers.

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  • ISO-Accredited Laboratory, Ensuring Highest Standards
  • Trusted by Hospitals & Patients —Accredited Testing with Results
  • Direct Healthcare Provider Support + Comprehensive Reporting
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PCSK1 Gene Obesity with Impaired Prohormone Processing NGS Genetic DNA Test

Understanding PCSK1 Gene Obesity and Prohormone Processing

The PCSK1 Gene Obesity with Impaired Prohormone Processing NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for severe obesity disorders. This specialized test focuses on identifying mutations in the PCSK1 gene, which encodes prohormone convertase 1/3 – a crucial enzyme responsible for processing multiple prohormones into their active forms. When this enzyme malfunctions due to genetic mutations, it disrupts the normal processing of hormones that regulate appetite, metabolism, and energy balance, leading to severe, early-onset obesity that often resists conventional weight management approaches.

What This Advanced Genetic Test Detects

Our comprehensive NGS-based genetic analysis specifically targets:

  • Pathogenic mutations in the PCSK1 gene affecting prohormone convertase 1/3 function
  • Genetic variants that impair the processing of key metabolic hormones including proinsulin, proglucagon, and proopiomelanocortin
  • Inherited genetic patterns associated with severe childhood-onset obesity
  • Specific mutation types that correlate with treatment response and clinical outcomes

Clinical Indications and Who Should Consider Testing

This specialized genetic test is particularly recommended for individuals presenting with:

  • Severe obesity developing in early childhood or infancy
  • Family history of extreme obesity across multiple generations
  • Obesity accompanied by endocrine abnormalities or metabolic disorders
  • Poor response to conventional diet, exercise, and pharmacological interventions
  • Associated symptoms including hyperphagia (excessive hunger), developmental delays, or hormonal imbalances
  • Unexplained weight gain patterns that don’t align with lifestyle factors

Comprehensive Benefits of PCSK1 Genetic Testing

Undergoing PCSK1 gene analysis provides multiple clinical advantages:

  • Personalized Treatment Planning: Results guide targeted therapeutic approaches specific to prohormone processing defects
  • Family Risk Assessment: Identifies genetic risk patterns for family members and future generations
  • Early Intervention Opportunities: Enables proactive management strategies before severe complications develop
  • Improved Diagnostic Clarity: Distinguishes genetic obesity from lifestyle-related weight issues
  • Enhanced Patient Understanding: Provides scientific explanation for challenging weight management cases

Understanding Your Genetic Test Results

Our comprehensive genetic counseling support helps you interpret your results:

  • Positive Result: Indicates presence of PCSK1 gene mutations; enables targeted treatment planning and family screening
  • Negative Result: Suggests alternative causes for obesity; guides further diagnostic evaluation
  • Variant of Uncertain Significance: Requires ongoing monitoring and potential family studies for clarification
  • Carrier Status: Important for reproductive planning and understanding inheritance patterns

Test Pricing and Availability

Test Component Price (USD)
Discount Price $500
Regular Price $700

Nationwide Testing Accessibility

We provide comprehensive PCSK1 genetic testing services across the United States with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your testing location.

Take Control of Your Genetic Health Today

Don’t let unexplained obesity control your life. Our PCSK1 Gene Obesity with Impaired Prohormone Processing NGS Genetic DNA Test provides the scientific clarity needed for effective, personalized weight management strategies. With results available in 3-4 weeks and comprehensive genetic counseling support, you’ll gain valuable insights into your unique genetic profile.

Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic test consultation and take the first step toward understanding your genetic predisposition to obesity.