NPM1 Gene Mutation Quantitative MRD Monitor Test
Comprehensive Introduction to NPM1 MRD Monitoring
The NPM1 Gene Mutation Quantitative MRD Monitor Test represents a groundbreaking advancement in leukemia management and precision medicine. This sophisticated molecular diagnostic tool is specifically designed to detect and quantify minimal residual disease (MRD) in patients with NPM1-mutated acute myeloid leukemia (AML). By leveraging cutting-edge Real Time PCR technology, this test provides hematologists and oncologists with unprecedented insights into treatment response and disease progression, enabling more informed clinical decisions and personalized treatment strategies.
What Does the NPM1 MRD Test Measure?
This advanced diagnostic test specifically targets and quantifies mutations in the Nucleophosmin 1 (NPM1) gene, which is one of the most common genetic alterations in adult acute myeloid leukemia. The test measures:
- Presence of NPM1 gene mutations with exceptional sensitivity
- Quantitative levels of mutant NPM1 transcripts
- Minimal residual disease burden during and after treatment
- Early indicators of disease recurrence before clinical symptoms appear
- Treatment response monitoring with molecular precision
Who Should Consider This Test?
The NPM1 Gene Mutation Quantitative MRD Monitor Test is recommended for:
- Patients diagnosed with NPM1-mutated acute myeloid leukemia
- Individuals undergoing chemotherapy or targeted therapy for AML
- Patients in remission to monitor for potential relapse
- Those experiencing unexplained symptoms following leukemia treatment
- Individuals with family history of hematological malignancies
- Patients requiring precise treatment response assessment
Clinical Indications and Symptoms
Patients presenting with symptoms such as persistent fatigue, unexplained bruising or bleeding, recurrent infections, bone pain, or abnormal blood counts should discuss this test with their hematologist or oncologist. Early detection and monitoring can significantly impact treatment outcomes and quality of life.
Key Benefits of NPM1 MRD Testing
This comprehensive monitoring solution offers numerous advantages for both patients and healthcare providers:
- Early Relapse Detection: Identifies disease recurrence before clinical symptoms manifest
- Treatment Optimization: Guides therapeutic decisions based on molecular response
- Prognostic Information: Provides valuable insights into long-term outcomes
- Personalized Medicine: Enables tailored treatment approaches
- Peace of Mind: Offers reassurance through regular monitoring
- Cost-Effective Care: Potentially reduces unnecessary treatments through precise monitoring
Understanding Your Test Results
Your NPM1 MRD test results will provide critical information about your leukemia status:
- Negative Result: Indicates no detectable NPM1 mutation, suggesting complete molecular remission
- Low-Level Positive: May indicate minimal residual disease requiring continued monitoring
- Increasing Levels: Suggests potential disease progression or relapse
- Quantitative Values: Provide precise measurement of mutation burden for trend analysis
It’s essential to discuss your results with your hematologist or oncologist, who will interpret them in the context of your overall clinical picture and treatment history.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| NPM1 Gene Mutation Quantitative MRD Monitor Test | $138 USD | $212 USD |
Sample Requirements and Processing
Sample Type: 5 mL (3 mL minimum) whole blood or bone marrow in 1 Lavender Top (EDTA) tube
Shipping Instructions: Ship refrigerated. DO NOT FREEZE
Turnaround Time: Samples accepted Monday/Thursday by 11 am; Reports available Wednesday/Saturday
Required Documentation: Duly filled MRD Requisition form (Form 22) with historical data is mandatory
Nationwide Availability
We have branches across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our extensive network ensures convenient access to this advanced leukemia monitoring technology for patients nationwide.
Take Control of Your Leukemia Management
Don’t leave your leukemia monitoring to chance. The NPM1 Gene Mutation Quantitative MRD Monitor Test provides the precision and reliability you need for optimal disease management. Our team of molecular diagnostics specialists and experienced laboratory professionals are committed to delivering accurate, timely results that empower you and your healthcare team to make informed decisions about your treatment journey.
Ready to Schedule Your Test?
Take the next step in your leukemia care by scheduling your NPM1 MRD monitoring test today. Our dedicated patient coordinators are available to answer your questions and help you book your appointment at a location convenient for you.
Call or WhatsApp us now at +1(267) 388-9828 to book your NPM1 Gene Mutation Quantitative MRD Monitor Test and take control of your leukemia management with precision molecular diagnostics.
