NANOS1 Gene Oligoasthenoteratozoospermia NGS Genetic DNA Test
Comprehensive Genetic Testing for Male Infertility
The NANOS1 Gene Oligoasthenoteratozoospermia NGS Genetic DNA Test represents a breakthrough in male reproductive health diagnostics. This advanced genetic screening utilizes cutting-edge Next-Generation Sequencing (NGS) technology to identify mutations in the NANOS1 gene that are directly linked to severe forms of male infertility. Understanding the genetic basis of fertility challenges provides couples with valuable information for making informed decisions about their reproductive journey and treatment options.
What Does This Test Measure and Detect?
This comprehensive genetic analysis specifically targets the NANOS1 gene, which plays a critical role in spermatogenesis – the process of sperm cell development. The test detects:
- Pathogenic variants and mutations in the NANOS1 gene
- Genetic markers associated with oligoasthenoteratozoospermia
- Inheritance patterns that may affect future generations
- Specific genetic abnormalities contributing to sperm production issues
Clinical Significance of NANOS1 Gene Mutations
The NANOS1 gene encodes proteins essential for proper germ cell development and maintenance. Mutations in this gene disrupt normal spermatogenesis, leading to the combined condition of oligozoospermia (low sperm count), asthenozoospermia (reduced sperm motility), and teratozoospermia (abnormal sperm morphology).
Who Should Consider This Genetic Test?
This test is particularly recommended for individuals experiencing:
- Unexplained male infertility with abnormal semen analysis results
- Family history of male infertility or reproductive challenges
- Recurrent pregnancy loss in couples
- Planning for assisted reproductive technologies (ART)
- Men with consistently poor semen parameters across multiple tests
Symptoms and Clinical Indicators
Patients presenting with the following symptoms may benefit from NANOS1 genetic testing:
- Persistently low sperm concentration (<15 million/mL)
- Reduced sperm motility (<40% progressive motility)
- High percentage of abnormally shaped sperm (>96%)
- Failed fertility treatments despite normal female partner evaluation
- Family history suggestive of genetic infertility patterns
Benefits of NANOS1 Genetic Testing
Undergoing this comprehensive genetic assessment offers numerous advantages:
- Accurate Diagnosis: Provides definitive genetic confirmation of the underlying cause of infertility
- Personalized Treatment Planning: Enables targeted fertility treatments based on genetic findings
- Genetic Counseling: Helps understand inheritance patterns and risks for future children
- Emotional Closure: Reduces uncertainty and provides answers for couples struggling with infertility
- Cost-Effective Approach: Prevents unnecessary treatments by identifying the root cause early
- Family Planning Guidance: Informs decisions about assisted reproductive technologies and genetic risks
Understanding Your Test Results
Our comprehensive genetic counseling service helps you interpret your results effectively:
Possible Result Interpretations
- Positive for NANOS1 Mutation: Confirms genetic cause of infertility, guiding specific treatment approaches
- Negative Result: Suggests other causes for infertility, directing further diagnostic evaluation
- Variant of Uncertain Significance: Requires additional family studies and ongoing research correlation
Clinical Implications
Positive results provide crucial information for reproductive specialists to recommend appropriate interventions, including:
- Targeted sperm retrieval techniques
- Preimplantation genetic testing options
- Donor sperm considerations
- Family planning strategies
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | NANOS1 Gene Oligoasthenoteratozoospermia NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
To ensure accurate results and comprehensive care, we require:
- Complete clinical history of the patient
- Genetic counseling session to create a detailed family pedigree chart
- Documentation of previous fertility evaluations and treatments
- Semen analysis reports when available
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and reproductive specialists ensures you receive consistent, high-quality care regardless of location.
Take the Next Step in Your Fertility Journey
Don’t let unanswered questions about male infertility prevent you from moving forward with your family planning goals. Our NANOS1 genetic test provides the clarity and direction needed to make informed decisions about your reproductive health.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your NANOS1 Gene Oligoasthenoteratozoospermia NGS Genetic DNA Test. Our compassionate team is ready to guide you through every step of the process with expertise and understanding.
Take control of your reproductive health today – discover the genetic insights that could transform your fertility journey and help you build the family you’ve been dreaming of.

