MT-TS1 Gene MERRF/MELAS Overlap Syndrome NGS Genetic DNA Test
Comprehensive Mitochondrial Disorder Genetic Testing
The MT-TS1 Gene MERRF/MELAS Overlap Syndrome NGS Genetic DNA Test represents a breakthrough in mitochondrial disease diagnostics, offering precise detection of genetic mutations responsible for complex neurological and metabolic disorders. This advanced testing methodology provides healthcare providers with critical information needed for accurate diagnosis and targeted treatment strategies.
What This Test Measures and Detects
This specialized genetic test focuses on identifying mutations in the MT-TS1 gene, which encodes mitochondrial transfer RNA for serine. The test specifically targets:
- Point mutations in the MT-TS1 mitochondrial gene
- Genetic variations associated with MERRF syndrome characteristics
- Mutations linked to MELAS syndrome features
- Overlap syndrome genetic markers
- Heteroplasmy levels in mitochondrial DNA
Using Next-Generation Sequencing technology, the test provides comprehensive analysis of the entire mitochondrial genome, ensuring high sensitivity and specificity in mutation detection.
Who Should Consider This Test
This genetic test is recommended for individuals presenting with symptoms suggestive of mitochondrial disorders, including:
- Patients with unexplained neurological symptoms including seizures, ataxia, or stroke-like episodes
- Individuals experiencing progressive muscle weakness and exercise intolerance
- Patients with elevated lactate levels in blood or cerebrospinal fluid
- Those with family history of mitochondrial disorders or unexplained neurological conditions
- Children or adults with developmental delays and multisystem involvement
- Patients with hearing loss, vision problems, or cardiac abnormalities of unknown origin
Clinical Benefits of MT-TS1 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out specific mitochondrial disorders
- Personalized Treatment: Enables targeted therapeutic interventions based on genetic findings
- Family Planning: Provides crucial information for genetic counseling and reproductive decisions
- Prognostic Information: Helps predict disease progression and potential complications
- Early Intervention: Facilitates timely management of symptoms and complications
- Research Contribution: Advances understanding of mitochondrial disease mechanisms
Understanding Your Test Results
Your genetic test results will be thoroughly explained by our genetic counseling team. Results typically fall into these categories:
- Positive Result: Identifies a pathogenic mutation in the MT-TS1 gene, confirming diagnosis of MERRF/MELAS overlap syndrome
- Negative Result: No mutations detected in the MT-TS1 gene, though other mitochondrial genes may need evaluation
- Variant of Uncertain Significance: Identifies genetic changes whose clinical significance requires further investigation
- Heteroplasmy Level: Indicates the percentage of mutated mitochondrial DNA, which can influence disease severity
Our genetic counselors provide comprehensive interpretation and guidance for next steps based on your specific results.
Test Pricing and Details
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
| Turnaround Time | 3-4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our network ensures accessible genetic testing services nationwide.
Take the Next Step Toward Diagnosis
If you or a loved one are experiencing symptoms that may indicate a mitochondrial disorder, don’t wait to get answers. Our comprehensive MT-TS1 genetic testing provides the clarity needed for proper diagnosis and management.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and test appointment. Our team of genetic specialists is ready to guide you through the testing process and help you understand your results.
Early diagnosis through advanced genetic testing can significantly impact treatment outcomes and quality of life for individuals with mitochondrial disorders. Take control of your health journey with precise, reliable genetic analysis from our certified laboratory.
